Results 61 to 70 of about 1,765,540 (254)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Semantic Fusion for Natural Multimodal Interfaces using Concurrent Augmented Transition Networks

Multimodal Technologies and Interaction, 2018
Semantic fusion is a central requirement of many multimodal interfaces. Procedural methods like finite-state transducers and augmented transition networks have proven to be beneficial to implement semantic fusion.
Chris Zimmerer, Martin Fischbach, Marc Erich Latoschik   +2 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Adaptive Real-Time Translation Assistance Through Eye-Tracking

AI
This study introduces the Eye-tracking Translation Software (ETS), a system that leverages eye-tracking data and real-time translation to enhance reading flow for non-native language users in complex, technical texts.
Dimosthenis Minas, Eleanna Theodosiou, Konstantinos Roumpas, Michalis Xenos   +3 more
doaj   +1 more source

Let’s Talk about TEX—Understanding Consumer Preferences for Smart Interactive Textile Products Using a Conjoint Analysis Approach

Sensors, 2018
Interactive textiles are reaching maturity. First technology augmented textiles in form of clothes and furnitures are becoming commercially available.
Julia Offermann-van Heek, Philipp Brauner, Martina Ziefle   +2 more
doaj   +1 more source

Effects of exposure to immersive computer-generated virtual nature and control environments on affect and cognition

Scientific Reports, 2023
Previous research has shown that exposure to immersive virtual nature environments is able to induce positive affective and physiological effects. However, research on the effects on cognitive performance is scarce.
Fariba Mostajeran, Marvin Fischer, Frank Steinicke, Simone Kühn   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

How deep is your trust? A comparative user requirements’ analysis of automation in medical and mobility technologies

Humanities & Social Sciences Communications
In a changing world full of innovative technologies, trust and trust requirements are increasingly important for designing user-centred systems and ensuring their long-term implementation.
Sophia Hick, Hannah Biermann, Martina Ziefle   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Eye-to-eye or face-to-face? Face and head substitution for co-located augmented reality

Frontiers in Virtual Reality
In co-located extended reality (XR) experiences, headsets occlude their wearers’ facial expressions, impeding natural conversation. We introduce two techniques to mitigate this using off-the-shelf hardware: compositing a view of a personalized avatar ...
Peter Kullmann, Theresa Schell, Mario Botsch, Marc Erich Latoschik   +3 more
doaj   +1 more source