Results 71 to 80 of about 720,543 (314)

Iterative Design and Evaluation of a Tangible Robot-Assisted Handwriting Activity for Special Education

Frontiers in Robotics and AI, 2020
In this article we investigate the role of interactive haptic-enabled tangible robots in supporting the learning of cursive letter writing for children with attention and visuomotor coordination issues.
Arzu Guneysu Ozgur, Ayberk Özgür, Thibault Asselborn, Wafa Johal, Elmira Yadollahi, Barbara Bruno, Barbara Bruno, Melissa Skweres, Pierre Dillenbourg   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multimodal Child-Robot Interaction: Building Social Bonds [PDF]

, 2013
07.01.14 KB. Ok to add published version to spiral, OA paper.For robots to interact effectively with human users they must be capable of coordinated, timely behavior in response to social context.
Cosi, Piero, Belpaeme, TonyTW068020022768090000-0001-5207-7745034899FA-C938-11E5-A139-C70DB5D1D7B1, Demiris, Yiannis, Enescu, Valentin, Neerincx, Mark, Ros-Espinoza, Raquel, Athanasopoulos, Georgios, Hiolle, Antione, Kruijff-Korbayová, Ivana, Belpaeme, Tony, Wood, Rachel, Humbert, Remi, Cuayáhuitl, Heriberto, Cañamero, Lola, Racioppa, Stefania, Read, Robin, Lewis, Matthew, Kiefer, Bernd, Beck, Aryel, Paci, Giulio, Baxter, Paul E, Sommavilla, Giacomo, Baroni, Ilaria, Tesser, Fabio, Nalin, Marco, Looije, Rosemarijn   +25 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

How deep is your trust? A comparative user requirements’ analysis of automation in medical and mobility technologies

Humanities & Social Sciences Communications
In a changing world full of innovative technologies, trust and trust requirements are increasingly important for designing user-centred systems and ensuring their long-term implementation.
Sophia Hick, Hannah Biermann, Martina Ziefle   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Adaptive Real-Time Translation Assistance Through Eye-Tracking

AI
This study introduces the Eye-tracking Translation Software (ETS), a system that leverages eye-tracking data and real-time translation to enhance reading flow for non-native language users in complex, technical texts.
Dimosthenis Minas, Eleanna Theodosiou, Konstantinos Roumpas, Michalis Xenos   +3 more
doaj   +1 more source

Semantic Fusion for Natural Multimodal Interfaces using Concurrent Augmented Transition Networks

Multimodal Technologies and Interaction, 2018
Semantic fusion is a central requirement of many multimodal interfaces. Procedural methods like finite-state transducers and augmented transition networks have proven to be beneficial to implement semantic fusion.
Chris Zimmerer, Martin Fischbach, Marc Erich Latoschik   +2 more
doaj   +1 more source