Results 61 to 70 of about 720,543 (314)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Magic NeRF lens: interactive fusion of neural radiance fields for virtual facility inspection

open access: yesFrontiers in Virtual Reality
Virtual reality (VR) has become an important interactive visualization tool for various industrial processes including facility inspection and maintenance.
Ke Li   +6 more
doaj   +1 more source

Applying IDC theory to education in the Alps region: a response to Chan et al.’s contribution

open access: yesResearch and Practice in Technology Enhanced Learning, 2019
In this paper, we present a response to the Interest-Driven Creator (IDC) theory from a European perspective. Specifically, we raise six questions intended to start a dialog with respect to IDC theory’s placement in existing learning theories, its ...
Pierre Dillenbourg   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Give the people what they want: studying end-user needs for enhancing the web [PDF]

open access: yesPeerJ Computer Science, 2016
End-user programming (EUP) is a common approach for helping ordinary people create small programs for their professional or daily tasks. Since end-users may not have programming skills or strong motivation for learning them, tools should provide what end-
Tak Yeon Lee, Benjamin B. Bederson
doaj   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Low-cost eye-tracking for human computer interaction

open access: yes, 2006
Knowing the user's point of gaze has long held the promise of being a useful methodology for human computer interaction. However, a number of barriers have stood in the way of the integration of eye tracking into everyday applications, including the ...
Li, Dongheng
core   +1 more source

Structural Monitoring using Engineer-Computer Interaction [PDF]

open access: yes, 2002
Engineer–computer interaction (ECI) is a new subdomain of human–computer interaction that is specifically tailored to engineers' needs. ECI uses an information classification schema, provides a modular approach to task decomposition, and integrates ...
Stalker, R.   +2 more
core   +1 more source

Systematic Review of Multimodal Human–Computer Interaction

open access: yes, 2022
This document presents a systematic review of Multimodal Human–Computer Interaction. It shows how different types of interaction technologies (virtual reality (VR) and augmented reality, force and vibration feedback devices (haptics), and tracking)
Julieta Noguez   +5 more
core   +1 more source

Motion-based user identification across XR and metaverse applications by deep classification and similarity learning

open access: yesFrontiers in Virtual Reality
This paper examines the generalization capacity of two state-of-the-art classification and similarity learning models in reliably identifying users from their motion patterns across diverse eXtended Reality (XR) applications. We introduce a novel dataset
Lukas Schach   +3 more
doaj   +1 more source

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