Results 61 to 70 of about 13,632,971 (306)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Applied SciencesTo develop truly human-centered automated systems, it is essential to acknowledge that human reasoning is prone to systematic deviations from rational judgment, known as Cognitive Biases.
Carina Manger +2 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Enabling Implicit Human Computer Interaction: A Wearable RFID-Tag Reader [PDF]
, 2000 Implicit human computer interaction is based on the concept of using user activity in the real world as input to computers. Implicit HCI can help to reduce the problem of user input to wearable computers.
Schmidt, Albrecht +2 more
core +3 more sources
Magic NeRF lens: interactive fusion of neural radiance fields for virtual facility inspection
Frontiers in Virtual RealityVirtual reality (VR) has become an important interactive visualization tool for various industrial processes including facility inspection and maintenance.
Ke Li +6 more
doaj +1 more source
Applying IDC theory to education in the Alps region: a response to Chan et al.’s contribution
Research and Practice in Technology Enhanced Learning, 2019 In this paper, we present a response to the Interest-Driven Creator (IDC) theory from a European perspective. Specifically, we raise six questions intended to start a dialog with respect to IDC theory’s placement in existing learning theories, its ...
Pierre Dillenbourg +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Effects of exposure to immersive videos and photo slideshows of forest and urban environments
Scientific Reports, 2021 A large number of studies have demonstrated the benefits of natural environments on people’s health and well-being. For people who have limited access to nature (e.g., elderly in nursing homes, hospital patients, or jail inmates), virtual representations
Fariba Mostajeran +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source