Results 101 to 110 of about 23,617 (297)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A methodology for operationalising the robot centric HRI paradigm : enabling robots to leverage sociocontextual cues during human-robot interaction [PDF]

, 2015
University of Technology Sydney. Faculty of Engineering and Information Technology.The presence of social robots in society is increasing rapidly as their reach expands into more roles which are useful in our everyday lives.
Caraian, SA
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Masked-speech Recognition Using Human and Synthetic Cloned Speech

Trends in Hearing
Voice cloning is used to generate synthetic speech that mimics vocal characteristics of human talkers. This experiment used voice cloning to compare human and synthetic speech for intelligibility, human-likeness, and perceptual similarity, all tested in ...
Lauren Calandruccio, Mohsen Hariri, Emily Buss, Vipin Chaudhary   +3 more
doaj   +1 more source

A physicochemical descriptor-based scoring scheme for effective and rapid filtering of kinase-like chemical space

Journal of Cheminformatics, 2012
Background The current chemical space of known small molecules is estimated to exceed 1060 structures. Though the largest physical compound repositories contain only a few tens of millions of unique compounds, virtual screening of databases of this size ...
Singh Narender, Sun Hongmao, Chaudhury Sidhartha, AbdulHameed Mohamed, Wallqvist Anders, Tawa Gregory   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Deep Video Generation, Prediction and Completion of Human Action Sequences

, 2017
Current deep learning results on video generation are limited while there are only a few first results on video prediction and no relevant significant results on video completion.
A Newell, A Odena, C Dong, C Ionescu, J Jia, J Johnson, J Walker, J-Y Zhu, L Wang, Olaf Ronneberger, R Zhang, RH Byrd, X Wang, Y Wexler, Z Wang   +14 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Digital Twin-Based Alternate Ego Modeling and Simulation: Eva Herzigová as a 3D MetaHuman Avatar

Engineering Management in Production and Services
Due to Dimension Studios and Unsigned Group, by likeness and movement digitization, the human supermodel Eva Herzigová’s highly realistic metahuman and 3D digital twin lead to perpetual career extension (e.g., on virtual runway shows by catwalk ...
Lăzăroiu George, Gedeon Tom, Szpilko Danuta, Halicka Katarzyna   +3 more
doaj   +1 more source