Results 91 to 100 of about 23,617 (297)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exploring the Effectiveness of Evaluation Practices for Computer-Generated Nonverbal Behaviour

open access: yesApplied Sciences
This paper compares three methods for evaluating computer-generated motion behaviour for animated characters: two commonly used direct rating methods and a newly designed questionnaire.
Pieter Wolfert   +2 more
doaj   +1 more source

Imago et similitudo Dei: op soek na die betekenis van die mens as beeld en gelykenis van God vanuit ’n Christelikfilosofiese hoek

open access: yesKoers : Bulletin for Christian Scholarship, 2008
Imago et similitudo Dei: the meaning of humans being God’s image and likeness investigated from a Christianphilosophical perspective This investigation is an effort to determine the meaning of the Biblical revelation that human beings were created in ...
B.J. van der Walt
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Challenges in Collaborative HRI for Remote Robot Teams [PDF]

open access: yes, 2019
Collaboration between human supervisors and remote teams of robots is highly challenging, particularly in high-stakes, distant, hazardous locations, such as off-shore energy platforms.
Ahmad, Muneeb   +8 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Judging Others by Your Own Standards: Attractiveness of Primate Faces as Seen by Human Respondents

open access: yesFrontiers in Psychology, 2018
The aspects of facial attractiveness have been widely studied, especially within the context of evolutionary psychology, which proposes that aesthetic judgements of human faces are shaped by biologically based standards of beauty reflecting the mate ...
Silvie Rádlová   +2 more
doaj   +1 more source

The Pteromorphic Angelology of the \u3cem\u3eApocalypse of Abraham\u3c/em\u3e [PDF]

open access: yes, 2009
The purpose of this article is to explore the anti-anthropomorphic features of the angelological developments in the Apocalypse of ...
Orlov, Andrei
core   +1 more source

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