Results 131 to 140 of about 266,906 (256)

Proof-of-Concept Human Organ-on-Chip Study: First Step of Platform to Assess Neuro-Immunological Communication Involved in Inflammatory Bowel Diseases. [PDF]

Int J Mol Sci, 2023
Gabriel-Segard T, Rontard J, Miny L, Dubuisson L, Batut A, Debis D, Gleyzes M, François F, Larramendy F, Soriano A, Honegger T, Paul S.   +11 more
europepmc   +1 more source

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

Advanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

Cholangiocarcinoma-on-a-chip: A human 3D platform for personalised medicine

JHEP Reports
Background & Aims: Cholangiocarcinoma (CCA) is a primary liver tumour characterised by a poor prognosis and limited therapeutic options. Available 3D human CCA models fail to faithfully recapitulate the tumour niche. We aimed to develop an innovative
Michela Anna Polidoro, Erika Ferrari, Cristiana Soldani, Barbara Franceschini, Giuseppe Saladino, Arianna Rosina, Andrea Mainardi, Francesca D’Autilia, Nicola Pugliese, Guido Costa, Matteo Donadon, Guido Torzilli, Simona Marzorati, Marco Rasponi, Ana Lleo   +14 more
doaj   +1 more source

Modelling Human Physiology on-Chip: Historical Perspectives and Future Directions. [PDF]

Micromachines (Basel), 2021
Pun S, Haney LC, Barrile R.
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Investigations on T cell transmigration in a human skin-on-chip (SoC) model. [PDF]

Lab Chip, 2021
Ren X, Getschman AE, Hwang S, Volkman BF, Klonisch T, Levin D, Zhao M, Santos S, Liu S, Cheng J, Lin F.   +10 more
europepmc   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Centrifugal Microfluidic Cell Culture Platform for Physiologically Relevant Virus Infection Studies: A Case Study with HSV-1 Infection of Periodontal Cells

Biosensors
Static well plates remain the gold standard to study viral infections in vitro, but they cannot accurately mimic dynamic viral infections as they occur in the human body.
Juliane Fjelrad Christfort, Morgane Ortis, Hau Van Nguyen, Robert Marsault, Alain Doglio   +4 more
doaj   +1 more source

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. [PDF]

Nat Commun, 2022
Bai H, Si L, Jiang A, Belgur C, Zhai Y, Plebani R, Oh CY, Rodas M, Patil A, Nurani A, Gilpin SE, Powers RK, Goyal G, Prantil-Baun R, Ingber DE.   +14 more
europepmc   +1 more source

THE FUTURE AND PROSPECTS OF BIO-CHIPS [PDF]

, 2014
Nanotechnology deals with manipulation of matter at atomic and molecular level. A general description for nanotechnology is provided by National Nanotechnology Initiative, that defines nanotechnology as the manipulation of matter with at least one ...
Pratibha, ., Raghu, Sukanya, S, Poornima, Shivakumar, Neeta   +3 more
core   +1 more source