Results 161 to 170 of about 2,199,898 (317)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A Human Health Perspective On Climate Change: A Report Outlining the Research Needs on the Human Health Effects of Climate Change [PDF]
This document addresses the abundant evidence of human activities altering the plant as witnessed through climate change and its effects on ...
United States. Department of Health and Human Services.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
, 1981 Annual report of the Texas Department of Human Resources describing goals, activities, and accomplishments during fiscal year ...
Texas. Department of Human Resources.
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
ESPACES MARINS : SURVEILLANCE ET PRÉVENTION DES TRAFICS ILLICITES EN MER
, 2016 International audienceMarine areas give rise to various ilegal actiities at sea: piracy and robbery, human trafficking and illegal immigration, drug trafficking, illegal fishing.
Chaumette, Patrick
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Human Resources Activities in Company
, 2011 The diploma thesis „Human Resources Activities in Company“ focuses on specification of personnel work in the Jiří Bláha company. Specifies individual human resources activities from a theoretical knowledge and compare it with reality, obtained in the ...
Matějíčková, Barbora
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A hierarchal framework for recognising activities of daily life
, 2009 PhDIn today’s working world the elderly who are dependent can sometimes be neglected by society. Statistically, after toddlers it is the elderly who are observed to have higher accident rates while performing everyday activities.
Usman Naeem, Naeem, Usman
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