Hybrid of Monkey and Human Adenoviruses [PDF]
Journal of Virology, 1968 Following joint replication of monkey SA7 adenovirus (C8 strain) and human adenovirus type 2 in green monkey kidney tissue culture, a virus possessing the properties of a hybrid was obtained. It was designated Ad2C8. Ad2C8 preparations contained two types of viral particles: human adenovirus type 2, and hybrid particles.
A D, Altstein +3 more
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Development of novel adenoviral vectors to overcome challenges observed with HAdV-5 based constructs [PDF]
, 2011 Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in pre-clinical models and clinical trials over the last two decades.
Julio Alonso-Padilla +215 more
core +4 more sources
Mating strategy is determinant of adenovirus prevalence in European bats.
PLoS ONE, 2020 Adenoviruses are double-strained DNA viruses found in a great number of vertebrates, including humans. In order to understand their transmission dynamics, it is crucial, even from a human health perspective, to investigate how host traits influence their
Federica Rossetto +10 more
doaj +1 more source
Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]
, 2014 Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W. +30 more
core +3 more sources
Adenoviruses in Fecal Samples from Asymptomatic Rhesus Macaques, United States
Emerging Infectious Diseases, 2012 Adenoviruses can cause infectious diarrheal disease or respiratory infections in humans; 2 recent reports have indicated probable human infection with simian adenoviruses (SAdVs).
Soumitra Roy +4 more
doaj +1 more source
Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway [PDF]
, 1993 Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional design
Curiel, David T. +5 more
core +2 more sources
The 5'UTR in human adenoviruses: leader diversity in late gene expression. [PDF]
Sci Rep, 2017 Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner.
Ramke M +5 more
europepmc +2 more sources
The Revolution in Viral Genomics as Exemplified by the Bioinformatic Analysis of Human Adenoviruses
Viruses, 2010 Over the past 30 years, genomic and bioinformatic analysis of human adenoviruses has been achieved using a variety of DNA sequencing methods; initially with the use of restriction enzymes and more currently with the use of the GS FLX pyrosequencing ...
Sarah Torres +3 more
doaj +1 more source
The Role of Hexon Protein as a Molecular Mold in Patterning the Protein IX Organization in Human Adenoviruses. [PDF]
J Mol Biol, 2017 Reddy VS.
europepmc +2 more sources