Results 101 to 110 of about 4,526 (199)

Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency: The role of DREAM in the maintenance of hESCs [PDF]

, 2016
Little is knownabout the functions of downstreamregulatory element antagonist modulator (DREAM) inembryonic stem cells (ESCs). However, DREAM interacts with cAMP response element-binding protein (CREB) in a Ca2+-dependent manner, preventing CREB ...
Aguilera, Yolanda, Capilla González, Vivian, Carrión Rodríguez, Ángel Manuel, Fontán Lozano, Ángela del Carmen, Hmadcha, Abdelkrim, Mellado, Nuria, Soria Escoms, Bernat   +6 more
core   +1 more source

hASC (human Adipose-derived Stem Cells) in bone tissue regeneration

, 2007
hASCs (human Adipose-derived Stem Cells) are very similar to MSCs from bone marrow and they are available more easily and in a larger amount. hASC are able to efficiently differentiate into osteogenic lineage and they show a very good in vitro adaptation to ceramic materials like HA and to Bio-Oss®: when they are seeded on it, they maintain their ...
L. de Girolamo, A.T. Brini, R. Weinstein
openaire   +1 more source

lncRNAs GAS5 and MALAT1 Contained in Human Adipose Stem Cell (hASC)-Derived Exosomes Drive the Cell-Free Repair and Regeneration of Wounds In Vivo

International Journal of Molecular Sciences
Wound healing progresses through four phases: hemostasis, inflammation, proliferation, and remodeling. Wounds may become chronic if this process is disrupted. The use of small extracellular vesicle (sEV; EVs < 200 nm) exosomes (exo; ~40–120 nm) derived from human adipose stem cells (hASCs) as a treatment for wounds is well studied.
Meredith Krause-Hauch, Rekha S. Patel, Bangmei Wang, Brenna Osborne, Brianna Jones, Paul Albear, Niketa A. Patel   +6 more
openaire   +2 more sources

Differences between the Proliferative Effects of Human Platelet Lysate and Fetal Bovine Serum on Human Adipose-Derived Stem Cells

Cells, 2019
Background: Recently, human adipose-derived stem cells (hASCs) were discovered in the human subcutaneous adipose tissue. PLTMax Human Platelet Lysate (PLTMax), a supplement refined from human platelets, has been reported to have proliferative effects on ...
Natsuko Kakudo, Naoki Morimoto, Yuanyuan Ma, Kenji Kusumoto   +3 more
doaj   +1 more source

Osteogenic differentiation of two distinct subpopulations of human adipose-derived stem cells: an in vitro and in vivo study [PDF]

, 2012
The first stem cells considered for the reconstruction of bone were bone marrow mesenchymal stem cells (BMSCs). Subsequently, cells with similar marker expression panel and differentiation potential were found in new sources of cells, such as adipose ...
Caetano-Lopes, da Silva, Ellies, Fraser, Fuchs, Fuchs, Fujimura, Gay, Gimble, Gimble, Gimble, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Hennrick, Huang, Hui, Jukola, Karsenty, Lee, Maes, Majore, Martins, Martins, McIntosh, Mochizuki, Ogawa, Oliveira, Planat-Benard, Puissant, Rada, Rada, Rada, Safford, Santos, Santos, Silva, Silva, Stains, Stock, Strem, Tuzlakoglu, Tuzlakoglu, Xu, Yamamoto, Yoshimura, Zeng, Zuk, Zuk   +52 more
core   +1 more source

Stem cell-containing hyaluronic acid-based spongy hydrogels for integrated diabetic wound healing [PDF]

, 2017
The detailed pathophysiology of diabetic foot ulcers is yet to be established and improved treatments are still required. We propose a strategy that directs inflammation, neovascularization, and neoinnervation of diabetic wounds. Aiming to potentiate a
Cerqueira, Mariana Teixeira, Correlo, V. M., Marques, A. P., Pirraco, Rogério P., Reis, R. L., Rodrigues, Daniel Barreira, Santos, T. C., Silva, Lucília Pereira   +7 more
core   +1 more source

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars.

PLoS ONE, 2016
Hypertrophic scars (HTS) are characterized by excessive amount of collagen deposition and principally occur following burn injuries or surgeries. In absence of effective treatments, the use of mesenchymal stem/stromal cells, which have been shown to ...
Sophie Domergue, Claire Bony, Marie Maumus, Karine Toupet, Eric Frouin, Valérie Rigau, Marie-Catherine Vozenin, Guy Magalon, Christian Jorgensen, Danièle Noël   +9 more
doaj   +1 more source

Single-cell derived clones from human adipose stem cells present different immunomodulatory properties [PDF]

, 2014
Human adipose mesenchymal stem cells are a heterogeneous population, where cell cultures derived from single cell-expanded clones present varying degrees of differential plasticity.
Arribas, María I., Fernández, Agustín F., Fraga, Mario F., Martínez-Peinado, Pascual, Reig, Juan A., Roche, Enrique, Santana, Alfredo, Sempere Ortells, José Miguel, Sen Fernández, María Luz de la, Zubcoff, Jose   +9 more
core   +2 more sources

Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors

Analytical Cellular Pathology, 2010
Carcinoma-associated fibroblasts (CAF) are considered to contribute to tumor growth, invasion and metastasis. However, the cell type of origin remains unknown.
Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao-Hua Song   +9 more
doaj   +1 more source

Neuroprotective effect of a cell-free extract derived from human adipose stem cells in experimental stroke models

Neurobiology of Disease, 2013
A recent study suggested that a cell-free extract of human adipose stem cells (hASCs-E) has beneficial effects on neurological diseases by modulating the host environment.
Daejong Jeon, Kon Chu, Soon-Tae Lee, Keun-Hwa Jung, Jae-Jun Ban, Dong-Kyu Park, Hye-Jin Yoon, Seungmoon Jung, Hyunwoo Yang, Byung Sun Kim, Ji Ye Choi, So Hee Kim, Jeong-Min Kim, Chong-Hyun Won, Manho Kim, Sang Kun Lee, Jae-Kyu Roh   +16 more
doaj   +1 more source