Results 151 to 160 of about 2,152,983 (311)

Inferring regulators of cell identity in the human adult pancreas. [PDF]

open access: yesNAR Genom Bioinform, 2023
Vanheer L   +16 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Moving close to parents and adult children in the Netherlands: the influence of support needs [PDF]

open access: yes
In this paper, the extent to which support needs lead to moves of adult children (aged 30 and above) to within one kilometer of their parents and vice versa is examined.
Annika Smits
core  

Critical Periods During Childhood and Adolescence: A Study of Adult Height Among Immigrant Siblings [PDF]

open access: yes
We identify the ages that constitute critical periods in children's development towards their adult health status. For this we use data on families migrating into Sweden from countries that are mostly poorer, with less healthy conditions. Long-run health
Rooth, Dan-Olof   +3 more
core   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Labor effects of adult mortality in Tanzanian households [PDF]

open access: yes
Due to the HIV/AIDS epidemic, sub-Saharan populations are challenged with increasing adult mortality rates that have potentially profound economic implications. Yet, little is known about the impact of adult deaths in African households. Using panel data
Beegle, Kathleen
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Working-Age Adult Mortality and Primary School Attendance in Rural Kenya

open access: yes
The rapid increase in adult mortality due to the AIDS epidemic in sub-Saharan Africa raises great concern about potential intergenerational effects on children.
Yamano, Takashi, Jayne, Thomas S.
core  

Evaluation of the Scottish Adult Literacy and Numeracy (ALN) Strategy - Final Report

open access: yes, 2006
The report evaluates the Scottish Adult Literacy and Numeracy (ALN) Strategy through a survey of a sample of literacy and numeracy learners and ALN tutors within 9 geographical areas in ...
Hall, Stuart   +4 more
core  

Home - About - Disclaimer - Privacy