Results 171 to 180 of about 10,928,650 (259)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

BSL - L2: Story: New Career Part 1

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Level 2 Stories – New ...
Lancashire Adult Learning
core  

Cyclin A2 induces cytokinesis in human adult cardiomyocytes and drives reprogramming in mice. [PDF]

NPJ Regen Med
Bouhamida E, Vadakke-Madathil S, Mathiyalagan P, Ranjan AK, Khan A, Sherman CD, Miller PE, Ghetti A, Abi-Gerges N, Chaudhry HW.   +9 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

BSL – L2 vocab: Travel and Holidays – Directions

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Vocabulary Level 2 Travel and Holidays ...
Lancashire Adult Learning
core  

An integrated single-cell and spatial proteotranscriptomics atlas of fibroblast-driven immunoregulation within the human adult oral cavity. [PDF]

Cell Press Blue
Matuck BF, Huynh KLA, Pereira D, Easter QT, Zhang X, Kunz M, Kumar N, Pratapa A, Rupp BT, Ghodke A, Predeus AV, Fernandes A, Szabó L, Hartmann S, Harnischfeger N, Khavandgar Z, Beach M, Perez P, Nilges B, Moreno MM, Ko KI, Singh R, Tata PR, Teichmann SA, Kimple A, Pringle S, Kretzschmar K, Warner BM, Sequeira I, Liu J, Byrd KM.   +30 more
europepmc   +1 more source

Scattered Tubular Cells Markers in Macula Densa of Normal Human Adult Kidney. [PDF]

Int J Mol Sci, 2022
Tossetta G, Fantone S, Lorenzi T, Galosi AB, Sagrati A, Fabri M, Marzioni D, Morroni M.   +7 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Modelling human adult V-SVZ niche assembly and ependymal cell generation in brain organoids. [PDF]

EMBO Rep
Vassalou S, Lalioti ME, Di Giaimo R, Taraviras S, Cappello S, Kyrousi C.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source