Results 171 to 180 of about 2,152,983 (311)

Unique information from common diffusion MRI models about white-matter differences across the human adult lifespan. [PDF]

Imaging Neurosci (Camb), 2023
Henriques RN, Henson R, Cam-CAN, Correia MM.   +3 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Adult Respiratory Syncytial Virus (RSV) Session [PDF]

01-RSV-Adult-Kotton-508 ...

core  

Differential Responses of Pediatric and Adult Primary Epithelial Cells to Human Metapneumovirus and Respiratory Syncytial Virus Infection

Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are pneumoviruses causing lower respiratory tract infections, primarily in infants and children rather than in healthy adults.
Antonieta Guerrero-Plata, Pius I. Babawale   +1 more
core   +1 more source

Expression spectrum of TE-driven transcripts in human adult tissues. [PDF]

Genome Biol
Miao B, Luo X, Ademovic A, Yang Y, Wu TP, Zhang BA.   +5 more
europepmc   +1 more source

Bioactivity of human adult stem cells and functional relevance of stem cell-derived extracellular matrix in chondrogenesis. [PDF]

Stem Cell Res Ther, 2023
Jiang Y, Tuan RS.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

HUMAN MESENCHYMAL STEM CELLS AS A MODEL OF STUDY FOR NEW BIOMATERIALS IN BONE TISSUE REGENERATION

, 2012
The reconstruction of large bone segments remains a critical clinical problem in the case of extensive bone loss due to traumatic or pathological events. Due to its ideal biocompatibility and osteogenic properties, autologous bone is still considered the
Manfrini, Marco
core  

Response to Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis". [PDF]

Science, 2022
Terreros-Roncal J, Moreno-Jiménez EP, Flor-García M, Rodríguez-Moreno CB, Trinchero MF, Márquez-Valadez B, Cafini F, Rábano A, Llorens-Martín M.   +8 more
europepmc   +2 more sources

Immortalization of Human Adult Alveolar Epithelial Cells to Study Environmental Exposures of the Distal Lung. [PDF]

Curr Protoc
Tran E, St Pierre L, Velarde D, Dal Bó B, Alvarez JR, Ofosu-Asante K, Lamango NS, Huang Y, Marconett CN, Borok Z, Zhou B, Offringa IA.   +11 more
europepmc   +1 more source