Results 1 to 10 of about 10,333 (209)

The burden of human African trypanosomiasis.

PLoS Neglected Tropical Diseases, 2008
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre, Beatrix V Wissmann, Susan C Welburn, Pascal Lutumba   +3 more
doaj   +7 more sources

Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia [PDF]

Emerging Infectious Diseases
We report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available.
Adugna Abera, Tihitina Mamecha, Ebise Abose, Belachew Bokicho, Agune Ashole, Tesfahun Bishaw, Abinet Mariyo, Buzayehu Bogale, Haileyesus Terefe, Henok Tadesse, Mahlet Belachew, Hailemariam Difabachew, Araya Eukubay, Solomon Kinde, Abraham Ali, Feyesa Regasa, Fikre Seife, Zeyede Kebede, Mesfin Wossen, Getachew Tollera, Mesay Hailu, Nigus Manaye, Nick Van Reet, Gerardo Priotto, Johan van Griensven, Myrthe Pareyn, Geremew Tasew   +26 more
doaj   +2 more sources

Diversity of human African trypanosomiasis epidemiological settings requires fine-tuning control strategies to facilitate disease elimination

Research and Reports in Tropical Medicine, 2013
PP Simarro,1 JR Franco,1 A Diarra,2 JA Ruiz Postigo,3 J Jannin11World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Regional Office for Africa,
Simarro PP, Franco JR, Diarra A, Ruiz Postigo JA, Jannin J   +4 more
doaj   +3 more sources

Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts

Virulence, 2023
African trypanosomes are vector-borne protozoa, which cause significant human and animal disease across sub-Saharan Africa, and animal disease across Asia and South America.
Liam J. Morrison, Pieter C. Steketee, Mabel D. Tettey, Keith R. Matthews   +3 more
doaj   +1 more source

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão, Cátia Ramalhete, Ana Margarida Madureira, Eduarda Mendes, Noélia Duarte   +4 more
doaj   +1 more source

Current Treatments to Control African Trypanosomiasis and One Health Perspective

Microorganisms, 2022
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei.
Alberto Venturelli, Lorenzo Tagliazucchi, Clara Lima, Federica Venuti, Giulia Malpezzi, George E. Magoulas, Nuno Santarem, Theodora Calogeropoulou, Anabela Cordeiro-da-Silva, Maria Paola Costi   +9 more
doaj   +1 more source

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +1 more source

Unusual neurological presentation of second stage African trypanosomiasis in a young boy: a case report

BMC Pediatrics, 2022
Background In South Sudan, sleeping sickness is a frequent condition caused by human African trypanosomiasis. There are two stages that are well-known.
Etedal Ahmed A. Ibrahim, Mohammed Gasm Elseed M. Elmahal, Khabab Abbasher Hussien Mohamed Ahmed, Elfatih A. Hasabo, Mohammed Eltahier Abdalla Omer   +4 more
doaj   +1 more source

Human African Trypanosomiasis Transmission, Kinshasa, Democratic Republic of Congo

Emerging Infectious Diseases, 2006
To investigate the epidemiology of human African trypanosomiasis (sleeping sickness) in Kinshasa, Democratic Republic of Congo, 2 entomologic surveys were conducted in 2005.
Gustave Simo, Philemon Mansinsa Diabakana, Victor Kande Betu Ku Mesu, Emile Zola Manzambi, Gaelle Ollivier, Tazoacha Asonganyi, Gerard Cuny, Pascal Grébaut   +7 more
doaj   +1 more source

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, Hamidou Ilboudo, V Pius Alibu, Sophie Ravel, John Enyaru, William Weir, Harry Noyes, Paul Capewell, Mamadou Camara, Jacqueline Milet, Vincent Jamonneau, Oumou Camara, Enock Matovu, Bruno Bucheton, Annette MacLeod   +14 more
doaj   +1 more source