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Human African trypanosomiasis & heart
Expert Review of Cardiovascular Therapy, 2020Human African Trypanosomiasis is a neglected tropical disease resulting from the infection with the parasite Trypanosoma brucei. Neurological compromise often dominates, and the impact of cardiovascular involvement has not been fully investigated. Recently, publications indicate that cardiovascular compromise is more frequent than previously thought ...
Hector Isaac Alejandro Ortiz +8 more
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2009
Human African trypanosomiasis (HAT) is caused by two subspecies of trypanosomes, Trypanosoma brucei gambiense and T.b. rhodesiense. Clinically, the disease is characterized by an early stage during which patients report non-specifi c symptoms such as fever and malaise, and trypanosomes are found in the blood or in lymph node aspirates.
Jacques Pépin, Honoré Méda
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Human African trypanosomiasis (HAT) is caused by two subspecies of trypanosomes, Trypanosoma brucei gambiense and T.b. rhodesiense. Clinically, the disease is characterized by an early stage during which patients report non-specifi c symptoms such as fever and malaise, and trypanosomes are found in the blood or in lymph node aspirates.
Jacques Pépin, Honoré Méda
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Neurology, 2006
Human African trypanosomiasis (HAT), which is also known as sleeping sickness, is a major cause of morbidity and mortality in 36 countries throughout sub-Saharan Africa. Two articles in this issue of Neurology serve as a reminder that this disease can be imported to other countries.1,2 It has been estimated that 60 million people are at risk of ...
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Human African trypanosomiasis (HAT), which is also known as sleeping sickness, is a major cause of morbidity and mortality in 36 countries throughout sub-Saharan Africa. Two articles in this issue of Neurology serve as a reminder that this disease can be imported to other countries.1,2 It has been estimated that 60 million people are at risk of ...
openaire +1 more source
Drug Resistance in Human African Trypanosomiasis
Future Microbiology, 2011Human African trypanosomiasis or 'sleeping sickness' is a neglected tropical disease caused by the parasite Trypanosoma brucei. A decade of intense international cooperation has brought the incidence to fewer than 10,000 reported cases per annum with anti-trypanosomal drugs, particularly against stage 2 disease where the CNS is involved, being central ...
Michael P, Barrett +4 more
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New developments in human African trypanosomiasis
Current Opinion in Infectious Diseases, 2006To review recent literature on human African trypanosomiasis, focussing on genome sequencing, diagnosis and drug discovery, and typing of trypanosomes.The most important recent development has been the completion of the Trypanosoma brucei genome which will greatly facilitate the discovery of new drug targets and genetic markers.
Brun, Reto, Balmer, Oliver
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Eflornithine for the treatment of human African trypanosomiasis
Parasitology Research, 2003Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. The most commonly used dosage regimen for the treatment of T. b.
Burri C, Brun R
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Human African trypanosomiasis–neurological aspects
Journal of Neurology, 2006Human African Trypanosomiasis (HAT),which is also known as sleeping sickness, is a major cause of death and disability in 36 countries in sub-Saharan Africa. The disease is caused by the protozoan parasite of the Trypanosoma genus which is transmitted by the bite of the tsetse fly.
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A current analysis of chemotherapy strategies for the treatment of human African trypanosomiasis
Pathogens and Global Health, 2013Adekunle Sanyaolu +2 more
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Diagnostic and neuropathogenesis issues in human African trypanosomiasis
International Journal for Parasitology, 2006Peter G E Kennedy
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