Results 151 to 160 of about 17,541,441 (365)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Internalized homophobia in homosexual men: a qualitative study

open access: yesDuazary, 2015
There is little evidence about linguistic expressions used that show internalized homophobia by homosexual individuals. The objective of this research was to explore suggestive internalized homophobic language used by web page users for homosocialization
Adalberto Campo-Arias   +2 more
doaj  

The value of intersectionality for genomic research on human behavior. [PDF]

open access: yesGenet Med, 2023
Matthews LJ   +2 more
europepmc   +1 more source

Behavior of cancers of the human lung in short-term tissue cultures [PDF]

open access: bronze, 1967
Russell P. Sherwìn   +2 more
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Private traits and attributes are predictable from digital records of human behavior

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Michal Kosinski   +2 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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