Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
SIRT3 activation protects from nabumetone-induced mitochondrial toxicity in adult human cardiomyocytes. [PDF]
Huang Y +14 more
europepmc +1 more source
Cardiac morphological and morphometric analysis of Ardea alba
Abstract Ardea alba (Linnaeus, 1758) is a widely distributed heron species whose cardiovascular morphology remains poorly described. This study aimed to characterize the cardiac morphology and morphometry of adult A. alba. Ten specimens were analyzed using radiographic, morphometric, histological, scanning electron microscopy, and three‐dimensional ...
Julia Vaz Feio +5 more
wiley +1 more source
Myocardial disarray drives metabolic inefficiency in human cardiomyocytes. [PDF]
Jouve C +14 more
europepmc +1 more source
Computational design of custom therapeutic cells to correct failing human cardiomyocytes. [PDF]
Tieu A +3 more
europepmc +1 more source
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang +8 more
wiley +1 more source
CX-5461 and doxorubicin activate a shared DNA damage-associated transcriptional response in human cardiomyocytes. [PDF]
Paul S +4 more
europepmc +1 more source
Propofol synergizes with circAPBB2 to protect against hypoxia/reoxygenation-induced oxidative stress, inflammation, and apoptosis of human cardiomyocytes. [PDF]
Jin C, Yuan S, Piao L, Ren M, Liu Q.
europepmc +1 more source
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu +12 more
wiley +1 more source
Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes. [PDF]
Haydar S +15 more
europepmc +1 more source

