Results 201 to 210 of about 113,516 (292)

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

MitoQ Protects Against Oxidative Stress-Induced Mitochondrial Dysregulation in Human Cardiomyocytes. [PDF]

J Mol Cell Cardiol Plus
Parker AM, Lees JG, Tate M, Phang RJ, Velagic A, Deo M, Bishop T, Krieg T, Murphy MP, Lim SY, De Blasio MJ, Ritchie RH.   +11 more
europepmc   +1 more source

Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes. [PDF]

iScience, 2022
Wu Q, Kumar N, Lafuse WP, Ahumada OS, Saljoughian N, Whetstone E, Zani A, Patton AK, El Refaey M, Webb A, Pietrzak M, Yu L, Kc M, Peeples ME, Ganesan LP, Yount JS, Rajaram MVS.   +16 more
europepmc   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Identification and validation of hypoxia-responsive signature pathways in human cardiomyocytes. [PDF]

3 Biotech
Sharma D, Karuna, Gupta H, Gupta A, Kumari M, Varshney R, Meena RC.   +6 more
europepmc   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Mitochondrial Protection by Astaxanthin Reduces Toxicity Caused by H₂O₂ and Doxorubicin in Human Cardiomyocytes. [PDF]

Cells
Baburina Y, Lomovsky A, Lomovskaya Y, Sotnikov R, Sotnikova L, Krestinina O.   +5 more
europepmc   +1 more source

Cell-Target-Specific Anti-Inflammatory Effect of Empagliflozin: In Vitro Evidence in Human Cardiomyocytes. [PDF]

Front Mol Biosci, 2022
Giannattasio S, Citarella A, Trocchianesi S, Filardi T, Morano S, Lenzi A, Ferretti E, Crescioli C.   +7 more
europepmc   +1 more source

Role of the ABA-LANCL1/2 hormone/receptors system in thermogenesis of cardiomyocytes and myoblasts

Abscisic acid (ABA) is a phytohormone conserved across kingdoms and also present in mammals, where it interacts with two receptors, LANCL1 and LANCL2 [1, 2].
Laura Sturla, Josè Gonzalez Urra Bujar Caushi Giovanni Zocchi Flavio Fontanelli Sonia Spinelli; Mario Passalacqua; Simona Delsante; Elena Zocchi   +1 more
core  

SPARCL1 and NT‐proBNP as biomarkers of right ventricular‐to‐pulmonary artery uncoupling in pulmonary hypertension

ESC Heart Failure, Volume 12, Issue 2, Page 1416-1426, April 2025.
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr, Stanislav Keranov, Paulina van Wickern, Holger Nef, Christian Hamm, Pascal Bauer, Christian Troidl, Samuel Sossalla, Sandra Voss, Christoph Liebetrau, Manuel J. Richter, Henning Gall, Werner Seeger, Ardeschir Ghofrani, Athiththan Yogeswaran, Khodr Tello   +15 more
wiley   +1 more source