Results 271 to 280 of about 113,516 (292)

Development of Cardiomyocytes from Human ES Cells

2003
Publisher Summary Cell transplantation is emerging as a novel strategy for myocardial regeneration, but it has been hampered by the lack of a source for human cardiomyocytes. Similarly, the lack of a human cardiomyocyte cell line has significantly limited a variety of experimental procedures.
Izhak, Kehat, Michal, Amit, Amira, Gepstein, Irit, Huber, Joseph, Itskovitz-Eldor, Lior, Gepstein   +5 more
openaire   +2 more sources

Cardiomyocytes from Human Embryonic Stem Cells

2006
Terminal heart failure is characterized by a significant loss of cardiac myocytes. Stem cells represent a possibility for replacing these lost myocytes but the question of which stem cells are most ideally suited for cell transplantation therapies is still being addressed.
R, Passier, C, Denning, C, Mummery
openaire   +2 more sources

Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract

Human Cell, 2011
Cell transplantation shows potential for the treatment of cardiac diseases. Embryonic stem cells, cord blood and mesenchymal stem cells have been suggested as sources for transplantation therapy. Because of some technical limitations with the use of stem cells, transdifferentiation of fully differentiated cells is a potentially useful alternative.
Zahra, Vojdani, Sima, Tavakolinejad, Tahereh, Talaei-Khozani, Tahereh, Esmaeilpour, Manuchehr, Rasooli   +4 more
openaire   +2 more sources

Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes

Molecular BioSystems, 2013
Abstract Fetal (fCM) and adult cardiomyocytes (aCM) significantly differ from each other both by structure and biochemical properties. aCM own a higher mitochondrial mass compared to fCM due to increased energy demand and show a greater density and higher degree of structural organization of myofibrils.
Jaakko L O, Pohjoismäki, Marcus, Krüger, Natalie, Al-Furoukh, Anssi, Lagerstedt, Pekka J, Karhunen, Thomas, Braun   +5 more
openaire   +2 more sources

[The ploidy variability of human cardiomyocytes].

Biulleten' eksperimental'noi biologii i meditsiny, 1990
Unlike literature on ploidy of the human myocytes, DNA content and the number of nuclei have been revealed in the same cells. Besides, the cell ploidy were studied separately in the external, central and inner regions in the left ventricule. Considerable binucleation was revealed in normal and hypertrophic ventricles where 4c X2 was the modal cell ...
V Ia, Brodskiĭ, I A, Vasil'eva, N V, Panova, D S, Sarkisov, A M, Aref'eva   +4 more
openaire   +1 more source

Reprogramming of human keratinocytes into functional cardiomyocytes

Italian Journal of Anatomy and Embryology, 2015
Purpose. Induced pluripotent stem cells (iPS) can be generated by patients intro- ducing transcription factors that are highly expressed in embryonic stem (ES) cells into somatic cells. However, the various iPS cell lines are characterized by different properties such as differentiation efficiency and potential safety hazards.
Ghinassi, Barbara, D’Amico, Maria, Izzicupo, Pascal, Di Baldassarre, Angela   +3 more
openaire   +1 more source

Cardiomyocyte renewal in humans.

Circulation Research
BERGMANN, O
openaire   +1 more source

Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

EMBO Molecular Medicine, 2015
Harsha D Devalla, Verena Schwach, David A Elliott   +2 more
exaly  

Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells

Circulation Research, 2002
Chunhui Xu, Melissa K Carpenter
exaly  

Highly enriched cardiomyocytes from human embryonic stem cells

Cytotherapy, 2008
Alan Colman, William Sun
exaly