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Thermoinactivation of Human Cytomegalovirus [PDF]
Journal of Bacteriology, 1966 Vonka, Vladimir (Baylor University College of Medicine, Houston, Tex.), and Matilda Benyesh-Melnick . Thermoinactivation of human cytomegalovirus. J. Bacteriol. 91: 221–226. 1966.—The inactivation at 4 and 37 C of several strains of human cytomegalovirus was studied.
Vladimı́r Vonka +1 more
openalex +3 more sources
MicroRNAs expressed by human cytomegalovirus [PDF]
Virology Journal, 2020 MicroRNAs (miRNAs) are small non-coding RNAs about 22 nucleotides in length, which play an important role in gene regulation of both eukaryotes and viruses.
Lichen Zhang, J. Yu, Zhijun Liu
semanticscholar +5 more sources
Human cytomegalovirus: taking the strain [PDF]
Medical Microbiology and Immunology, 2015 In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV), we reflect on the merits and limitations of the viral strains currently being used to develop urgently needed treatments.
G. Wilkinson +11 more
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The Transcriptome of Latent Human Cytomegalovirus [PDF]
Journal of Virology, 2019 The latent human cytomegalovirus (HCMV) transcriptome has been extremely difficult to define due to the scarcity of naturally latent cells and the complexity of available models. The genomic era offers many approaches to transcriptome profiling that hold
M. Schwartz, Noam Stern-Ginossar
semanticscholar +4 more sources
Sleepless latency of human cytomegalovirus [PDF]
Medical Microbiology and Immunology, 2015 As with all human herpesviruses, human cytomegalovirus (HCMV) persists for the lifetime of the host by establishing a latent infection, which is broken by periodic reactivation events.
E. Poole, J. Sinclair
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Vaccination against the human cytomegalovirus
Vaccine, 2019 The human cytomegalovirus (HCMV) is the most important infectious cause of congenital abnormalities and also of infectious complications of transplantation. The biology of the infection is complex and acquired immunity does not always prevent reinfection.
S. Plotkin, S. Boppana
semanticscholar +3 more sources
The pathogenesis of human cytomegalovirus
The Journal of Pathology, 2015 AbstractHuman cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general population.
P. Griffiths, I. Baraniak, M. Reeves
semanticscholar +4 more sources
Human cytomegalovirus and neonatal infection. [PDF]
Curr Res Microb SciHuman cytomegalovirus is an ancient virus that has co-evolved with humans. It establishes a life-long infection in suspectable individuals for which there is no vaccination or cure. The virus can be transmitted to a developing fetus in seropositive pregnant women, and it is the leading cause of congenital infectious disease.
Lawrence SM.
europepmc +4 more sources
Pathogenesis of human cytomegalovirus in the immunocompromised host
Nature Reviews Microbiology, 2021 Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild ...
P. Griffiths, M. Reeves
semanticscholar +1 more source
High-Risk Oncogenic Human Cytomegalovirus
Viruses, 2022 Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the population worldwide, usually without symptoms. The host immune response keeps the virus in a latent stage, although HCMV can reactivate in an inflammatory context ...
G. Herbein
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