Results 1 to 10 of about 204,523 (143)

Effect of host telomerase inhibition on human cytomegalovirus [PDF]

Journal of Virology
Treatment options remain limited for human cytomegalovirus (HCMV). Host telomerase has been implicated in the pathogenesis and oncogenesis of multiple herpesviruses, most recently including HCMV.
Chloe M. Cavanaugh, Cora N. Betsinger, Nicole Katchur, Sherry Zhang, Karen Yang, Maciej Nogalski, Ileana M. Cristea, Daniel Notterman   +7 more
doaj   +2 more sources

Control of human cytomegalovirus replication by liver resident natural killer cells

Nature Communications, 2023
Natural killer cells play important roles in the immune response to human cytomegalovirus infection. Here the authors implicate donor-derived liver resident natural killer cells in the control of human cytomegalovirus infection by analysis of perfusates ...
Calum Forrest, Thomas J. G. Chase, Antonia O. Cuff, Dionas Maroulis, Reza Motallebzadeh, Amir Gander, Brian Davidson, Paul Griffiths, Victoria Male, Matthew Reeves   +9 more
doaj   +1 more source

FREQUENCY OF HUMAN CYTOMEGALOVIRUS AND HUMAN HERPESVIRUS-1 ANTIGENS IN PRODUCT OF CONCEPTUS TISSUES OF PREGNANT WOMEN WITH SPONTANEOUS ABORTION

The Iraqi Journal of Medical Sciences, 2017
Background: Viral infections in pregnancy are major causes of maternal and fetal morbidity and mortality. Infections develop in the neonate transplacentally, perinatally or postnatally.
Areej A. Hussein, Sawsan T. Salman, Basim M. Khashman   +2 more
doaj   +6 more sources

Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection

Haematologica, 2008
Background Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation.
Daniele Lilleri, Chiara Fornara, Antonella Chiesa, Daniela Caldera, Emilio Paolo Alessandrino, Giuseppe Gerna   +5 more
doaj   +1 more source

High-Risk Oncogenic Human Cytomegalovirus

Viruses, 2022
Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the population worldwide, usually without symptoms. The host immune response keeps the virus in a latent stage, although HCMV can reactivate in an inflammatory context ...
Georges Herbein
doaj   +1 more source

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca, Cardi, Veronica, DE CURTIS, Mario, Fabio, Natale, Gaeta, Aurelia, Giuseppina, Liuzzi, Paola, Villani   +6 more
core   +2 more sources

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice, Hai, Rong, Li, Hongjian, Liu, Fenyong, Rider, Paul, Umamoto, Sean   +5 more
core   +3 more sources

Simultaneous monitoring of CMV and human herpesvirus 6 infections and diseases in liver transplant patients: one-year follow-up

Clinics, 2011
OBJECTIVE: The aim of this study was to simultaneously monitoring cytomegalovirus and human herpesvirus 6 active infections using nested-polymerase chain reaction and, together with clinical findings, follow the clinical status of patients undergoing ...
Fernanda Aparecida Costa, Marcelo Naoki Soki, Paula Durante Andrade, Sandra Helena Alves Bonon, Ronaldo Luis Thomasini, Ana Maria Sampaio, Marcelo de Carvalho Ramos, Claudio Lúcio Rossi, Teresa Cristina Cavalcanti, Ilka de Fatima Boin, Marília Leonard, Luiz Sérgio Leonard, Raquel Bello Stucchi, Sandra Cecília Botelho Costa   +13 more
doaj   +1 more source

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling, AB Rickinson, ARM Townsend, ARM Townsend, B Roizman, BT Rouse, C Taswell, deSt Fazekas, DR Mayo, G Berke, GM Keil, GV Quinnan, JB Hudson, JD Meyers, JD Shanley, JE Grundy, JK Chantler, JR Bennink, JR Marks, LK Borysiewicz, LR Gooding, M Ho, Matthias J. Reddehase, MC Jordan, MF Stinski, MJ Bevan, MJ Imperiale, MJ Reddehase, MJ Reddehase, MR Green, PG Spear, RJ Watson, RM Stenberg, RW Honess, SS Tevethia, UH Koszinowski, Ulrich H. Koszinowski   +36 more
core   +1 more source

Systematic microRNA analysis identifies ATP6V0C as an essential host factor for human cytomegalovirus replication.

PLoS Pathogens, 2013
Recent advances in microRNA target identification have greatly increased the number of putative targets of viral microRNAs. However, it is still unclear whether all targets identified are biologically relevant.
Jon Pavelin, Natalie Reynolds, Stephen Chiweshe, Guanming Wu, Rebecca Tiribassi, Finn Grey   +5 more
doaj   +1 more source