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MicroRNAs expressed by human cytomegalovirus [PDF]

open access: yesVirology Journal, 2020
Background MicroRNAs (miRNAs) are small non-coding RNAs about 22 nucleotides in length, which play an important role in gene regulation of both eukaryotes and viruses.
Lichen Zhang, Jiaqi Yu, Zhijun Liu
doaj   +5 more sources

Human cytomegalovirus and neonatal infection [PDF]

open access: yesCurrent Research in Microbial Sciences
Human cytomegalovirus is an ancient virus that has co-evolved with humans. It establishes a life-long infection in suspectable individuals for which there is no vaccination or cure.
Shelley M. Lawrence
doaj   +4 more sources

Thermoinactivation of Human Cytomegalovirus [PDF]

open access: bronzeJournal of Bacteriology, 1966
Vonka, Vladimir (Baylor University College of Medicine, Houston, Tex.), and Matilda Benyesh-Melnick . Thermoinactivation of human cytomegalovirus. J. Bacteriol. 91: 221–226. 1966.—The inactivation at 4 and 37 C of several strains of human cytomegalovirus was studied.
Vladimı́r Vonka   +1 more
openalex   +3 more sources

Human cytomegalovirus: taking the strain [PDF]

open access: yesMedical Microbiology and Immunology, 2015
In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV), we reflect on the merits and limitations of the viral strains currently being used to develop urgently needed treatments.
G. Wilkinson   +11 more
semanticscholar   +6 more sources

The Transcriptome of Latent Human Cytomegalovirus [PDF]

open access: yesJournal of Virology, 2019
The latent human cytomegalovirus (HCMV) transcriptome has been extremely difficult to define due to the scarcity of naturally latent cells and the complexity of available models. The genomic era offers many approaches to transcriptome profiling that hold
M. Schwartz, Noam Stern-Ginossar
semanticscholar   +4 more sources

Sleepless latency of human cytomegalovirus [PDF]

open access: yesMedical Microbiology and Immunology, 2015
As with all human herpesviruses, human cytomegalovirus (HCMV) persists for the lifetime of the host by establishing a latent infection, which is broken by periodic reactivation events.
E. Poole, J. Sinclair
semanticscholar   +5 more sources

Vaccination against the human cytomegalovirus

open access: yesVaccine, 2019
The human cytomegalovirus (HCMV) is the most important infectious cause of congenital abnormalities and also of infectious complications of transplantation. The biology of the infection is complex and acquired immunity does not always prevent reinfection.
S. Plotkin, S. Boppana
semanticscholar   +3 more sources

The pathogenesis of human cytomegalovirus

open access: yesThe Journal of Pathology, 2015
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general ...
P. Griffiths, I. Baraniak, M. Reeves
semanticscholar   +4 more sources

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

open access: yesHaematologica, 2016
We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted ...
Letizia Muccio   +9 more
doaj   +2 more sources

Human Cytomegalovirus and Autoimmune Disease [PDF]

open access: yesBioMed Research International, 2014
Human cytomegalovirus (HCMV) represents a prototypic pathogenic member of the β-subgroup of the herpesvirus family. A range of HCMV features like its lytic replication in multiple tissues, the lifelong persistence through periods of latency and ...
A. Halenius, H. Hengel
semanticscholar   +5 more sources

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