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Overview of Human Cytomegalovirus Pathogenesis.
Methods in molecular biology, 2021Heather L. Fulkerson+3 more
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Human Cytomegalovirus and Atherogenesis
1993The frequent finding of cytomegalovirus (CMV) antigens and nucleic acid sequences in arterial smooth muscle cells suggests that infection of the arterial wall may be common in patients with atherosclerosis. Immunosuppressive treatment of heart transplant patients often leads to CMV infection.
Ervin Adam+2 more
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Human cytomegalovirus virion proteins
Human Immunology, 2004Human cytomegalovirus (HCMV) is the largest member of the family of human herpesviruses. The number of virus encoded proteins and the complexity of their functions in the life cycle of this virus are reflected in the size of its genome. There continues to be some controversy surrounding the exact protein coding capacity of the virus with estimates ...
William J. Britt, Suresh B. Boppana
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Variants of Human Cytomegalovirus
1982Antigenic variations of human cytomegaloviruses were first detected by cross-neutralization tests. Weller et al. (1960) reacted sera from two babies (named Davis and Esp.) with isolates from themselves, with isolates from each other, and with AD169, an isolate from adenoids (Rowe et al., 1956).
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Consequences of human cytomegalovirus mimicry
Human Immunology, 2004The HCMV genome has evolved with its host by incorporating a series of genes that are homologous to, or functionally mimic, cellular genes. Some are designed to counteract the stress of infection on the host cell, notably the viral antiapoptotic proteins (vICA, vMIA). Others potentially help the infected cell maintain a low immunologic profile.
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Human Cytomegalovirus and the Neutrophil
2018Medical Research Council Research Clinical Fellowship Addenbrooke's Charitable ...
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Human cytomegalovirus and immunopathology
Springer Seminars in Immunopathology, 2002Mark R. Wills+4 more
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Human cytomegalovirus vaccines
2007Efforts to develop a human cytomegalovirus (HCMV) vaccine began more than 30 years ago in response to then recent reports that HCMV was capable of causing severe congenital disease. During the intervening years, our understanding of HCMV biology and immunology has increased dramatically.
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Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Nature Immunology, 2018Quirin Hammer+24 more
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Control of Apoptosis by Human Cytomegalovirus
2008Caspase-dependent apoptosis has an important role in controlling viruses, and as a result, viruses often encode proteins that target this pathway. Caspase-dependent apoptosis can be activated from within the infected cell as an intrinsic response to replication-associated stresses or through death-inducing signals produced extrinsically by immune cells.
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