Results 31 to 40 of about 100,666 (169)
Haematologica, 2016 We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted ...
Letizia Muccio +9 more
doaj +1 more source
Frontiers in Nutrition, 2022 Pasteurized donor human milk is recommended for hospitalized preterm infants when mother’s own milk is unavailable. Our aim was to compare the antiviral activity of human milk processed by Holder pasteurization (HoP) or high-pressure processing (HPP ...
Akash Kothari +17 more
doaj +1 more source
The Oncogenicity of Human Cytomegalovirus [PDF]
, 2013 The potential role of Human cytomegalovirus (hCM) infection in promoting neoplasia is an active area of scientific research. [1] Although still controversial, there is a growing body of evidence that links hCMV infection to a variety of malignancies, including those of the breast, prostate, colon, lung and brain (gliomas).
David M. Aboulafia, Prakash Vishnu
openaire +3 more sources
Human cytomegalovirus persistence
Cellular Microbiology, 2012 Viral persistence is the rule following infection with all herpesviruses. The β-herpesvirus, human cytomegalovirus (HCMV), persists through chronic and latent states of infection. Both of these states of infection contribute to HCMV persistence and to the high HCMV seroprevalence worldwide.
Patricia Zagallo +2 more
openaire +3 more sources
Modification of Specific Regions of the Human Cytomegalovirus Genome During in Vitro Passage
Canadian Journal of Infectious Diseases, 1990 Different regions of the human cytomegalovirus strain AD-169 DNA molecule were tested for stability using cloned Hind III fragments. Results indicate that insertion, deletion and/or rearrangement of nucleotide sequences occur at a relatively high ...
Claude Hamelin, Michel Dion
doaj +1 more source
Towards a Prophylactic Vaccine for the Prevention of HCMV Infection
Vaccines, 2021 Human cytomegalovirus (HCMV) or human herpesvirus 5, is a ubiquitous human herpesvirus, which can cause severe disease in immunocompromised patients (AIDS patients and solid organ transplant or hematopoietic stem cell transplant recipients) [...]
Gaëtan Ligat +2 more
doaj +1 more source
Dynamic Kernel Matching for Non-conforming Data: A Case Study of T-cell Receptor Datasets [PDF]
arXiv, 2021 Most statistical classifiers are designed to find patterns in data where numbers fit into rows and columns, like in a spreadsheet, but many kinds of data do not conform to this structure. To uncover patterns in non-conforming data, we describe an approach for modifying established statistical classifiers to handle non-conforming data, which we call ...
arxiv
Cytomegalovirus (CMV) Infection and Latency
Pathogens, 2021 Cytomegalovirus (CMV) is a herpesvirus that infects a majority of the human population worldwide [...]
Christine M. O’Connor
doaj +1 more source
A Noisy-Label-Learning Formulation for Immune Repertoire Classification and Disease-Associated Immune Receptor Sequence Identification [PDF]
arXiv, 2023 Immune repertoire classification, a typical multiple instance learning (MIL) problem, is a frontier research topic in computational biology that makes transformative contributions to new vaccines and immune therapies. However, the traditional instance-space MIL, directly assigning bag-level labels to instances, suffers from the massive amount of noisy ...
arxiv
Intermittent bulk release of human cytomegalovirus.
PLoS Pathogens, 2022 Human Cytomegalovirus (HCMV) can infect a variety of cell types by using virions of varying glycoprotein compositions. It is still unclear how this diversity is generated, but spatio-temporally separated envelopment and egress pathways might play a role.
Felix J Flomm +9 more
doaj +3 more sources