Results 261 to 270 of about 109,393 (302)
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NATURAL KILLER CELLS ACTIVATE HUMAN DERMAL FIBROBLASTS
Cytokine, 2000Human dermal fibroblasts (HDF) undergo activation and secrete cytokines when cocultured with T cells. Here, we identify potent activators of HDF among human peripheral CD2(+)-lymphocytes. Populations with strong HDF activating capacity consisted essentially of cells with a natural killer (NK) surface marker phenotype (CD3(-), CD4(-), CD8(-), CD56 ...
K M, Müller +3 more
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Stimulation of Human Dermal Fibroblasts with Interleukin 2
Journal of Burn Care & Rehabilitation, 1991The role of soluble inflammatory mediators in the wound healing process is under investigation. Interleukin 2 (IL2), an immune modulator produced by T lymphocytes, was tested in vitro for its effects on human diploid fibroblasts. Human diploid fibroblasts (1.0 x 10(4)) were incubated for 24 hours in Alpha minimal essential media (Gibco Laboratories ...
A, Abdullah, R L, McCauley, D N, Herndon
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Isolation and Culture of Human Dermal Fibroblasts
2019Dermal fibroblasts are the main cell type present in skin connective tissue (dermis). Fibroblasts interact with epidermal cells during hair development and in interfollicular skin. Moreover, they play an essential role during cutaneous wound healing and in bioengineering of skin. Hence, culture of primary fibroblast is gaining in importance.
Marta A, Kisiel, Agnes S, Klar
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UVB irradiation on human dermal fibroblasts
2023UVB is a primary contributor to extrinsic skin aging, and a comprehensive understanding of its impact on human skin is crucial for elucidating the aging process and facilitating the development of effective drug treatments. Additionally, UVB plays a pivotal role in vitamin D synthesis within dermal fibroblasts, underscoring its positive effects on ...
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IL-4 Induces Eotaxin in Human Dermal Fibroblasts
International Archives of Allergy and Immunology, 1999A common feature of Th2-mediated skin diseases is selective eosinophil (Eo) infiltration in the affected dermis. However, the mechanisms of selective Eo recruitment are not yet fully understood. Our recent findings indicated that dermal fibroblasts actively participate in the accumulation of Eo in Th2-mediated skin inflammation.
M, Mochizuki +3 more
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Characterization of Human Dermal Fibroblasts in Fabry Disease
Journal of Cellular Physiology, 2015Fabry disease (FD) is a hereditary X‐linked metabolic lysosomal storage disorder due to insufficient amounts or a complete lack of the lysosomal enzyme α‐galactosidase A (α‐GalA). The loss of α‐GalA activity leads to an abnormal accumulation of globotriaosylcerami (Gb3) in lysosomes and other cellular components of different tissues and cell types ...
LAKOMA, JARMILA +3 more
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Effects of Tamoxifen on Normal Human Dermal Fibroblasts
Archives of Facial Plastic Surgery, 2006To evaluate the effects of tamoxifen on the growth and autocrine growth factor production of human dermal fibroblasts from the face.In vitro study of normal adult dermal fibroblast cells developed from surgical specimens in a serum-free model. Cell cultures were exposed to 5-, 8-, 12-, 16-, and 50-microg/mL concentrations of tamoxifen solution.
Mauro B, Ruffy +2 more
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Lactoferrin promotes hyaluronan synthesis in human dermal fibroblasts
Biotechnology Letters, 2010Bovine lactoferrin (BLF) enhanced production of hyaluronan in normal human dermal fibroblasts. The elevation of hyaluronan was accompanied by elevation of HAS2 (hyaluronan synthase 2) mRNA transcription and HAS2 protein expression. The promoting effect of BLF was not observed for HAS1.
Shinichi, Saito +3 more
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Contractility of single human dermal myofibroblasts and fibroblasts
Cell Motility, 2002AbstractHuman dermal myofibroblasts, characterised by the expression of α‐smooth muscle actin, are part of the granulation tissue and implicated in the generation of contractile forces during normal wound healing and pathological contractures. We have compared the contractile properties of single human dermal fibroblasts and human dermal myofibroblasts
Louise K, Wrobel +5 more
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Differentiation of human dermal fibroblasts towards endothelial cells
Differentiation, 2013The ultimate goal of vascular tissue engineering is the production of functional grafts for clinical use. Difficulties acquiring autologous endothelial cells have motivated the search for alternative cell sources. Differentiation of dermal fibroblasts towards several mesenchymal lineages as well as endothelial cells has been proposed.
Johan P E, Junker +5 more
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