Results 21 to 30 of about 514,219 (199)
Frontiers in Human Neuroscience, 2014 Objectives: After stroke a typical presentation is exaggerated stretch reflexes (SR) on the more affected (MA) side. The present study evaluated the contribution of presynaptic inhibition (PSI) induced by arm cycling and homosynaptic depression (HD) to ...
Rinaldo André Mezzarane +7 more
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Evolutionary psychology: the emperor’s new paradigm [PDF]
, 2005 For some evolutionary psychology is merely a field of inquiry, but for others it is a robust paradigm involving specific theories about the nature and evolution of the human mind.
Buller, David J.
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Discovery of Novel Human Aquaporin-1 Blockers [PDF]
ACS Chemical Biology, 2012 Human aquaporin-1 (hAQP1) is a water channel found in many tissues and potentially involved in several human pathologies. Selective inhibitors of hAQP1 are discussed as novel treatment opportunities for glaucoma, brain edema, inflammatory pain, and certain types of cancer.
Seeliger, Daniel +7 more
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Frontiers in Pharmacology, 2023 The inefficiency of existing animal models to precisely predict human pharmacological effects is the root reason for drug development failure. Microphysiological system/organ-on-a-chip technology (organ-on-a-chip platform) is a microfluidic device ...
Naina Sunildutt +4 more
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Systematic discovery of endogenous human ribonucleoprotein complexes [PDF]
Cell Reports, 2018 AbstractRNA-binding proteins (RBPs) play essential roles in biology and are frequently associated with human disease. While recent studies have systematically identified individual RBPs, their higher order assembly intoRibonucleoprotein (RNP) complexes has not been systematically investigated.
Anna L. Mallam +10 more
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BMJ Global Health, 2020 Objective The emergence of infectious diseases pose major global health threats. Estimates of total in-country human pathogen diversity, and insights as to how and when species were described through history, could be used to estimate the probability of ...
Paul N Newton +5 more
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BMC Medical Genetics, 2012 Background Technological leaps in genome sequencing have resulted in a surge in discovery of human disease genes. These discoveries have led to increased clarity on the molecular pathology of disease and have also demonstrated considerable overlap in the
Duda Marlena +2 more
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Chronobiology: Discovery of the molecular mechanisms of circadian rhythm
Journal of Mental Health and Human Behaviour, 2018 Advances in the field chronobiology have potential implications for physical as well as mental health and human behavior. Several paradigm-shifting discoveries established key mechanistic principles for the biological clock.
Pooja Shakya +2 more
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On the growth of scientific knowledge: yeast biology as a case study. [PDF]
PLoS Computational Biology, 2009 The tempo and mode of human knowledge expansion is an enduring yet poorly understood topic. Through a temporal network analysis of three decades of discoveries of protein interactions and genetic interactions in baker's yeast, we show that the growth of ...
Xionglei He, Jianzhi Zhang
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The therapeutic aspects of the endocannabinoid system (ECS) for cancer and their development: from nature to laboratory [PDF]
, 2016 The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells.
Botta, Bruno +5 more
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