Results 51 to 60 of about 155,859 (254)

How does cold water impact on human physiology? Recent research discoveries

Journal of Education, Health and Sport
  We analysed the newest research conducted from 2019 to 2023. The study was searched in the online databases, especially in PubMed. Results: The newest studies are not consistent with the impact of cold water after training sessions on muscle ...
Wiktor Wróblewski, Paweł Zalewski, Dariusz Gruca, Adam Raabe, Marcin Wais   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Kantian discoveries in the field of human sciences: their importance for education [PDF]

, 2010
RESUMEN: Resaltando el alto nivel de difusión de los descubrimientos en el campo de las ciencias naturales,el texto muestra algunos de los descubrimientos kantianos en el campo de las ciencias humanas y presenta un análisis sobre la importancia de estos ...
Ríos Acevedo, Clara Inés
core  

Presentation: Human Mating Strategies

, 2013
What are the motivations behind mating desires in men and women? To understand many differences and conflicts between the sexes, we must look into our evolutionary past. During this Hot Science – Cool Talks, Dr.
Buss, David, Environmental Science Institute   +1 more
core   +1 more source

Objective Analysis of Movement Behaviours and Cardiometabolic Health in Sub‐Saharan Africans Living in the UK: A Cross Sectional Study

Health Science Reports
Background and Aims Movement behaviours, including sedentary behaviour (SB), physical activity (PA), and sleep, play a crucial role in cardiometabolic health.
Damilola A. Ibirogba, Luis S. Andalco, Matteo Crotti, Sarah J. Charman, Amy S. Fuller, Titilope Ajepe, Michael Duncan, Alasdair P. Blain, Faatihah Niyi‐Odumosu, Peter W. Mwangi, Federick O. Bukachi, Olufumilola L. Dominic, Otto F. Barak, Djordje G. Jakovljevic, Nduka C. Okwose   +14 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Genomics and the Prevention and Control of Common Chronic Diseases: Emerging Priorities for Public Health Action

Preventing Chronic Disease, 2005
The completion of the Human Genome Project in 2003 continues to raise expectations on near-term applications of human genome discoveries in personalized disease prevention, especially in the area of common chronic diseases (1,2). In fact, almost daily we
George A. Mensah, MD, Muin J. Khoury, MD, PhD   +1 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Current Challenges and Future Prospects in Human Reproduction and Infertility

Medicina
Human reproduction is a captivating yet intricate field, constantly presenting new challenges and discoveries [...]
Laurie Henry, Michelle Nisolle
doaj   +1 more source