Results 61 to 70 of about 155,859 (254)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Social Work Discoveries. Episode 3, Part 1:Human Rights and Social Work Research with Professor Linda Briskman

open access: yes, 2017
Welcome to Social Work Discoveries. A podcast on social work, research, and making the world a better place. My name is Ben Joseph. And I’m so glad you’ve made it here! This is great!
Briskman, Linda (R18870)   +1 more
core  

New discoveries of human fossils in the middle pleistocene site of Atapuerca/Ibeas

open access: yes, 1990
Arsuaga J.L., Carretero J.M., Gracia A., Martinez I. New discoveries of human fossils in the middle pleistocene site of Atapuerca/Ibeas. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, Nouvelle Série. Tome 2 fascicule 1, 1990. pp.
Martinez, I.   +3 more
core   +1 more source

Uterine Natural Killer Cell Heterogeneity: Lessons From Mouse Models

open access: yesFrontiers in Immunology, 2020
Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Dorothy K. Sojka
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Social Work Discoveries. Episode 3, Part 2: Human Rights and Social Work Research with Professor Linda Briskman

open access: yes, 2017
Welcome to Social Work Discoveries. A podcast on social work, research, and making the world a better place. My name is Ben Joseph. And I’m so glad you’ve made it here! This is great!
Briskman, Linda (R18870)   +1 more
core  

Comparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs

open access: yesVeterinary Sciences, 2015
Osteosarcoma (OS) is a primary and aggressive bone sarcoma affecting the skeleton of two principal species, human beings and canines. The biologic behavior of OS is conserved between people and dogs, and evidence suggests that fundamental discoveries in ...
Timothy M. Fan, Chand Khanna
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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