Results 81 to 90 of about 155,859 (254)
The fifth era of science: Artificial scientific intelligence.
PLoS BiologyThe era of artificial scientific intelligence is here. As algorithms generate discoveries at scale, what role remains for human scientists?
Nina Miolane
doaj +1 more source
New discoveries of Middle Paleolithic human remains from the “Bau de l'Aubésier (Vaucluse, France)”
Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2001 Excavations in Middle Paleolithic levels at the “Bau de l’Aubésier (Vaucluse)” during 2000 yielded a maxillary molar and a partial mandible from late Middle Pleistocene levels, plus a maxillary molar from the early Late Pleistocene.
Serge Lebel, Erik Trinkaus
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The stuff of life: What the human genome discoveries portend for human health
, 2001 book review of LIFE SCRIPT: HOW THE HUMAN GENOME DISCOVERIES WILL TRANSFORM MEDICINE AND ENHANCE YOUR HEALTH, by Nicholas ...
Comfort, Nathaniel C.
core
Genomics Reaches the Clinic: From Basic Discoveries to Clinical Impact
, 2011 Today, more than ever, basic science research provides significant opportunities to advance our understanding about the genetic basis of human disease. Close interactions among laboratory, computational, and clinical research communities will be crucial ...
Green, Eric D. +3 more
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HRIS project teams skills and knowledge: a human capital analysis
, 2009 Digital advancements and discoveries are now challenging traditional human resource management services within businesses. The Handbook of Research on E-Transformation and Human Resources Management Technologies: Organizational Outcomes and Challenges ...
Williams, H. +11 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modeling the behavior of human induced pluripotent stem cells seeded on melt electrospun scaffolds
, 2017 Background Human induced pluripotent stem cells (hiPSCs) can form any tissue found in the body, making them attractive for regenerative medicine applications.
Mohtaram, Nima K +10 more
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