Results 71 to 80 of about 155,859 (254)
The Bohemian Bookshelf : supporting serendipitous discoveries through visualization
Serendipity, a trigger of exciting discoveries when we least expect it, is currently being discussed as an often neglected but still important factor in information seeking processes, research, and ideation.
Thudt, Alice +2 more
core
Discoveries in Human Biology Through Kinase Signaling [PDF]
Kinases are signaling proteins that are involved in many different cellular processes. There are over 500 different kinases to accomplish these various tasks. Abnormal kinase signaling can lead to severe disease outcomes.
Moss, Steven Michael
core
The Middle Paleolithic Anthropological Discoveries in the 19th Century
The Middle Paleolithic Anthropological Discoveries in the 19th Century. The paleoanthropological discoveries of the 19th century, even though rare, generated a huge interest in the scientific world.
Nicolae, Adrian
core +1 more source
On Teams, Teamwork, and Team Performance: Discoveries and Developments
Objective: We highlight some of the key discoveries and developments in the area of team performance over the past 50 years, especially as reflected in the pages of Human Factors.
Salas, Eduardo +5 more
core +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Challenges of EEG in Coma: The Potential of Recent Discoveries
The utilization of electroencephalography (EEG) has profoundly enriched our comprehension and monitoring of patients, especially those in intensive care units (ICUs), over the past decades. EEG, a method of recording electrical brain signals, is employed
Mili, Lamine M., Hbibi, Bechir
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New discoveries and re-discoveries of human remains from the late Middle Pleistocene (
Amélie Vialet +10 more
doaj +1 more source
Port d’Entrée for Respiratory Infections – Does the Influenza A Virus Pave the Way for Bacteria?
Bacterial and viral co-infections of the respiratory tract are life-threatening and present a global burden to the global community. Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes are frequent colonizers of the upper ...
Nikolai Siemens +6 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

