Results 61 to 70 of about 12,340,655 (258)

Human embryonic stem cells and patent protection [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2015
Given the importance of biotechnological research in modern diagnostics and therapeutics, on the one hand, and stimulative function of a patent, on the other hand, this work deals with the question of the possibility of pa-tent protection of human ...
Radovanović Sanja M.
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Sorting live stem cells based on Sox2 mRNA expression. [PDF]

, 2012
PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Hans M. Larsson (118208), Frey Peter, Larsson, H.M., Velluto, Diana, Hans M. Larsson, Jeffrey A. Hubbell (118232), Roccio Marta, Velluto Diana, Lee, S.T., Hubbell, Jeffrey A., Jeffrey A. Hubbell, Roccio, Marta, Peter Frey (118226), Lee, ST, Roccio, M, Matthias P Lutolf, Lutolf, MP, Velluto, D., Larsson, Hans M., Matthias P. Lutolf (118222), Lutolf, M.P., Frey, P., Larsson Hans M., Jeffrey A Hubbell, Seung Tae Lee, Lutolf Matthias P., Marta Roccio, Hubbell Jeffrey A., Larsson, HM, Velluto, D, Diana Velluto (118218), Peter Frey, Matthias P. Lutolf, Hubbell, JA, Lutolf, Matthias P., Hubbell, J.A., Lee Seung Tae, Roccio, M., Frey, Peter, Lee, Seung Tae, Marta Roccio (118214), Diana Velluto, Hans M Larsson, Seung Tae Lee (118211), Frey, P, Larsson HM, Frey P, Lutolf MP, Hubbell JA, Velluto D, Roccio M, Lee ST   +51 more
core   +3 more sources

Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State

Stem Cells International, 2021
Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5 ...
A. S. Devika, Anna Montebaur, S. Saravanan, Raghu Bhushan, Frederic Koch, Smita Sudheer   +5 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D, Suzuki, H., Forrest, Alistair R. R., Hasegawa, Y., Suzuki, H, Ovchinnikov, Dmitry A., Hitchens, Kelly J., Takahashi, N., Forrest, A.R.R., Kenna, Tony, Suzuki, Harukazu, Tang, D., Joshi, Anagha, Hayashizaki, Y., Wolvetang, Ernst, Tang, Dave, Suzuki, H., Forrest, Alistair R R, FANTOM Consortium, the FANTOM consortium, Vijayan, Dipti, Wells, Christine A., Hasegawa, Y, Hayashizaki, Yoshihide, Forrest, ARR, Takahashi, Naoko, Briggs, James, Hasegawa, Yuki, Blumenthal, Antje, Tang, D., Hayashizaki, Y, ?, ?, Sajantila, Antti, Hasegawa, Y., Takahashi, N, Takahashi, N., Forrest, A. R., Beckhouse, Anthony G., FANTOM Consortium,, Hayashizaki, Y.   +39 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Brief Report-Human Embryonic Stem Cell-Derived Mesenchymal Progenitors Possess Strong Immunosuppressive Effects toward Natural Killer Cells as Well as T Lymphocytes

, 2010
The derivation of mesenchymal progenitors from human embryonic stem cells (hESCs) has recently been reported. We studied the immune characteristics of these hESC-derived mesenchymal progenitors (EMPs) and their interactions with T lymphocytes and natural
顏伶汝;劉柯俊;陳耀昌;胡欣怡;白其卉;嚴孟祿, YEN, BETTY LIN-JU;LIU, KO-JIUNN;CHEN, YAO-CHANG;HU, HSIN-I;BAI, CHYI-HUEY;YEN, MENG-LUH   +1 more
core   +1 more source

Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation [PDF]

, 2009
Objectives:  Defects of the mitochondrial genome (mtDNA) cause a series of rare, mainly neurological disorders. In addition, they have been implicated in more common forms of movement disorders, dementia and the ageing process.
Turnbull, Doug, Trevelyan, Andrew, Smulders-Srinivasan, Tora, Rennie, Katherine, Acin-Perez, Rebecca, Enriquez, J. A., Rennie, K. J., Lightowlers, R. N., Smulders-Srinivasan, T. K.; id_orcid, Kirby, D. M., Whittington, M., Trevelyan, A. J., Turnbull, D. M., Acin-Perez, R., Kirby, Denise, Lightowlers, Robert, Whittington, Miles, Enriquez, Jose   +17 more
core   +1 more source

Progress in Stem Cell Frontier

Journal of the Dow University of Health Sciences, 2012
Human life starts when a sperm combines with an  ovum and forms a fertilised egg. This cell and its immediate descendents, are called "totipotent stem cells".
Tahir Shamsi
doaj   +4 more sources