Results 71 to 80 of about 12,340,655 (258)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Tenogenic differentiation of human embryonic stem cells [PDF]

, 2018
Tendon healing is complex to manage because of the limited regeneration capacity of tendon tissue; stem cell-based tissue engineering approaches may provide alternative healing strategies.
Maffulli, N., Forsyth, N., El Haj, A., Chen, G., Zhou, J., Mazher, S., Webb, R., Dale, T.   +7 more
core   +1 more source

Recent Advances towards the Clinical Application of Stem Cells for Retinal Regeneration

Cells, 2012
Retinal degenerative diseases constitute a major cause of irreversible blindness in the world. Stem cell-based therapies offer hope for these patients at risk of or suffering from blindness due to the deterioration of the neural retina.
G. Astrid Limb, Hari Jayaram, Silke Becker   +2 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Aseptic and automatable vitrification of human embryonic stem cells using defined media [PDF]

, 2012
This talk reports on progress and achievements of University of Liège (coordinator) and Glycomar company for developping a novel technology for cryopreserving human embryonic stem cells intended for therapeutic use in cell-bases regenerative thérapies ...
Ectors, Fabien, Connan, Delphine, Grobet, Luc   +2 more
core   +1 more source

MOUSE AND HUMAN EMBRYONIC STEM CELLS

Вавиловский журнал генетики и селекции, 2014
This mini review is focused on the current state in the field of mouse and human embryonic stem (ES) cell biology. Methods of ES cell derivation, pluripotency assessment and problems associated with long term cultivating in vitro are discussed. Attention
A. G. Menzorov
doaj  

A Method to Identify and Isolate Pluripotent Human Stem Cells and Mouse Epiblast Stem Cells Using Lipid Body-Associated Retinyl Ester Fluorescence

Stem Cell Reports, 2014
We describe the use of a characteristic blue fluorescence to identify and isolate pluripotent human embryonic stem cells and human-induced pluripotent stem cells.
Thangaselvam Muthusamy, Odity Mukherjee, Radhika Menon, Megha Prakash Bangalore, Mitradas M. Panicker   +4 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization [PDF]

, 2012
Embryonic stem cells derived from nuclear transfer embryos (ntESCs) are particularly valuable for regenerative medicine, as they are a patient-specific and histocompatible cell source for the treatment of varying diseases.
Julianna Kobolak, Ruttachuk Rungsiwiwut, Andras Dinnyes, Mamo, Solomon, Ujhelly, Olga, Csonka, Erika, Solomon Mamo, Hadlaczky, Gyula, Olga Ujhelly, Gyula Hadlaczky, Kobolak, Julianna, Dinnyes, Andras, Erika Csonka, Rungsiwiwut, Ruttachuk   +13 more
core   +1 more source

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

npj Aging and Mechanisms of Disease, 2017
Regenerative medicine: lacrimal gland epithelium in vitro One possible approach to treat dry eye diseases is to transplant lacrimal glands generated in vitro from human embryonic stem cells into patients.
Masatoshi Hirayama, Shigeru B.H. Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K. Goparaju, Atsumi Soma, Yuhki Nakatake, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeto Shimmura, Kazuo Tsubota, Minoru S.H. Ko   +11 more
doaj   +1 more source