Results 101 to 110 of about 17,528,888 (291)

The social perception of performance enhancement and body modification: A systematic review and meta-analysis on anabolic steroids, tattoos, and cosmetic surgery

Acta Psychologica
To our knowledge, few studies have attempted to explore the social perception of targets engaged in performance enhancement and body modification, and none has done so through a systematic review and meta-analysis.
Hailemariam Weldemariam, Razieh Chegeni, Ståle Pallesen, Gunnar Breivik, Sigmund Loland, Dominic Sagoe   +5 more
doaj   +1 more source

Is human enhancement intrinsically bad? [PDF]

Med Health Care Philos, 2021
Kudlek K.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transhumanism and its Genesis: The Shaping of Human Enhancement Discourse by Visions of the Future

Humana.Mente: Journal of Philosophical Studies, 2014
Current discourse on human enhancement is strongly influenced by far-reaching, radical visions concerning the future of human corporeality and civilisation.
Christopher Coenen
doaj  

'Beyond' Human Enhancement - Taking the Developing Country's Perspective Seriously. [PDF]

Asian Bioeth Rev, 2022
Sachdev V.
europepmc   +1 more source

Transhumanism Between Human Enhancement and Technological Innovation

, 2016
: Transhumanism introduces from its very beginning a paradigm shift about concepts like human nature, progress and human future. An overview of its ideology reveals a strong belief in the idea of human enhancement through technologically means.
I. Iuga
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Unveiling the right to self-transformation and self-enhancement: exploring Transhumanism and its impact on human rights and the future of humanity

Deusto Journal of Human Rights
The time to discuss, contemplate and philosophize about Transhumanism has inevitably come. Thanks to technology which continues to transform human lives in enormous ways.
Lisang Nyathi
doaj   +1 more source

The final frontier: what is distinctive about the bioethics of space missions? The cases of human enhancement and human reproduction. [PDF]

Monash Bioeth Rev, 2023
Szocik K, Reiss MJ.
europepmc   +1 more source