Results 71 to 80 of about 31,425 (209)
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Advanced Science, EarlyView.Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Prognostic significance of human epididymis protein 4 in epithelial ovarian cancer
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2011 The purpose of this study was to evaluate the prognostic significance of serum human epididymis protein 4 (HE4) level in patients with epithelial ovarian cancer.A total of 78 women diagnosed with a pelvic mass and operated on in our institute comprised our cohort.
Jiheum, Paek +7 more
openaire +3 more sources
Antimicrobial peptides: agents of border protection for companion animals. [PDF]
, 2012 Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers
Advanced Science, EarlyView.This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu +9 more
wiley +1 more source
Frontiers in Oncology, 2018 Human epididymis protein 4 (HE4) is an important clinical biomarker used for the detection of epithelial ovarian cancer (EOC). While much is known about the predictive power of HE4 clinically, less has been reported regarding its molecular role in the ...
Nicole E. James +3 more
doaj +1 more source
Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]
, 2018 The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
core +1 more source
Advanced Science, EarlyView.Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An +11 more
wiley +1 more source
Hamidiye Medical JournalBackground: Human epididymis protein 4 (HE4) was discovered in 1991 as a glycoprotein secreted from the cells of the human epididymal epithelium and associated with sperm development and immunity.
Pınar Öksüz +4 more
doaj +1 more source
Serum HE4 Detects Ovarian Cancer Recurrence Earlier Than CA 125: Indian Study [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Recurrence is a frequent phenomenon of the natural history of epithelial Ovarian Cancer (OC). Early detection of recurrence is important.
Naseem Akhtar +7 more
doaj +1 more source
Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease. [PDF]
, 2018 Sexual transmission of Ebola virus (EBOV) has been demonstrated more than a year after recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying EBOV persistence and sexual transmission are not currently understood.
Bernbaum, John G. +7 more
core +1 more source