Results 51 to 60 of about 31,425 (209)

An update on the potential for male contraception : emerging options [PDF]

, 2013
The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Alsaadi, Manal, Ferro, Valerie, Garside, Deborah A, Gebril, Ayman M, Mullen, Alexander, Nimmo, Natalie   +5 more
core   +1 more source

A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]

, 2015
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco, DE ROOIJ, DIRK GIJSBERT, Di Cecca, Stefano, DI GIACOMO, Monica, DI SIENA, Sara, Faieta, Monica, Luchetti, Andrea, Murdocca, Michela, Pellegrini, Manuela, Rossi, Pellegrino   +9 more
core   +3 more sources

Evaluation of HE4 as a prognostic biomarker in uterine cervical cancer,

Cancer Treatment and Research Communications, 2023
Introduction: Uterine cervical cancer (UCC) is the fourth most common health problem worldwide among women. Currently available biomarkers CA125, CA199, and CEA for diagnosis or prognostic evaluation of UCC have not got widespread acceptance.
Harshita Dubey, Amar Ranjan, Julieana Durai, M.A. Khan, R. Lakshmy, Sachin Khurana, Swati Gupta, Jyoti Meena, M.D. Ray, Pranay Tanwar, Anita Chopra, Sanat Tiwari   +11 more
doaj   +1 more source

Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas [PDF]

Human Pathology, 2013
Upper gastrointestinal neoplasia in the esophagus, stomach, and pancreas is associated with the formation of preneoplastic metaplasias. We have previously reported the up-regulation of human epididymis protein 4 (HE4) in all metaplasias in the stomach of humans and mice.
Ryan L, O'Neal, Ki Taek, Nam, Bonnie J, LaFleur, Brittney, Barlow, Koji, Nozaki, Hyuk-Joon, Lee, Woo Ho, Kim, Han-Kwang, Yang, Chanjuan, Shi, Anirban, Maitra, Elizabeth, Montgomery, M Kay, Washington, Wael, El Rifai, Ronny I, Drapkin, James R, Goldenring   +14 more
openaire   +3 more sources

Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa [PDF]

, 2017
It has been suggested that the energy required for sperm motility is produced by oxidative phosphorylation while glycolysis seems to be an important source for ATP transmission along the flagellum.
Coltrinari, Giulia, Gallo, Mariagrazia, Gandini, Loredana, Lenzi, Andrea, Lombardo, Francesco, Paoli, Donatella, Pelloni, Marianna   +6 more
core   +1 more source

The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer

Open Medicine, 2016
To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
doaj   +1 more source

Clinical Usefulness of Human Epididymis Protein 4 in Lung Cancer

Annals of Laboratory Medicine, 2017
Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker of lung cancer; however, few relevant large-scale studies have been published. In this study, we evaluated the utility of serum HE4 for lung cancer detection. HE4 levels were measured in serum samples from 100 lung cancer patients, 57 patients with benign lung diseases, and ...
Choi, Soo In, Jang, Mi-Ae, Jeon, Byung Ryul, Shin, Hee Bong, Lee, You Kyoung, Lee, Yong-Wha   +5 more
openaire   +2 more sources

Exploring the relationship between preeclampsia and human epididymis protein 4

Journal of Surgery and Medicine, 2022
Background/Aim: The level of human epididymis protein 4 (HE4), a glycoprotein and protease inhibitor,increases under many malignancies and inflammatory conditions. HE4 is also associated with cellinvasion, migration, and adhesion. In this study, we compared the HE4 protein levels in pregnant patientswith preeclampsia to healthy pregnant and non ...
Yilmaz, Emsal Pinar Topdagi, Halici, Zekai, Borekci, Bunyamin, Cimilli Şenocak, Gamze Nur   +3 more
openaire   +3 more sources

Evaluation of tumor marker HE4 assay on the Elecsys 2010 analyzer

Journal of Health Sciences, 2014
Introduction: Whey-acidic protein human epididymis protein 4 (HE4) is a new promising biomarker for epithelial ovarian cancer. The measured HE4 values may depend on the testing procedure used.
Jozo Ćorić, Lejla Hasanbegović, Aleksandar Bodulović, Jasminka Mujić   +3 more
doaj   +1 more source

Evaluation of Vascular Complication and Lack of Glycemic Control as Factors in the Development of Ovarian Cancer in Female Nigerian Type 2 Diabetic Population

Journal of Applied Sciences and Environmental Management, 2023
Hypertension and diabetes are important medical conditions that are responsible for a significant number of deaths globally. Therefore, the objective of this study was to assess the human epididymis protein-4 in patients with untreated and treated ...
O. O. Odewusi, I. S. Egede, A. E. Omon, S. O. Obadire, Z. T. Sokunbi   +4 more
doaj   +1 more source