Results 61 to 70 of about 201,143 (234)
O Mundo da Saúde, 2014 The present article is the result of a bibliographical survey that seeks to present, by using a methodology based on the hypothetical-deductive method, to present a reflection on the biotechnological advances taking in consideration the vulnerability of ...
Angelita Maria Maders
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Future Internet, 2017 As Augmented Reality (AR) applications become commonplace, the determination of a device operator’s subjective Quality of Experience (QoE) in addition to objective Quality of Service (QoS) metrics gains importance. Human subject experimentation is common
Brian Bauman, Patrick Seeling
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
BEHAVIOR OF HUMAN‐IMPRINTED AND HEN‐REARED WILD TURKEY POULTS
Wildlife Society Bulletin, 1975 Behavior patterns are described for human‐imprinted and hen‐reared wild turkey poults (Meleagris gallopavo silvestris) from hatching until 4 months of age. Poults fed primarily on insects during the first 5 weeks of life.
William M. Healy +2 more
doaj +1 more source
Frontiers in Immunology, 2019 This perspective outlines an approach to improve mechanistic understanding of macrophages in inflammation and tissue homeostasis, with a focus on human inflammatory bowel disease (IBD).
Joanneke E. Jansen +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Informed consent in experimentation involving mentally impaired persons: ethical issues
Annali dell'Istituto Superiore di Sanità, 2010 The problem of experimentation involving subjects whose mental condition prevents them from understanding information and providing proper informed consent has been addressed in various codes, declarations, conventions, treaties and regulations adopted ...
Carlo Petrini
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source