Results 101 to 110 of about 9,687,585 (343)

EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis

open access: yesBreast Cancer Research
Background Despite progress understanding the mechanisms underlying tumor spread, metastasis remains a clinical challenge. We identified the choline-producing glycerophosphodiesterase, EDI3 and reported its association with metastasis-free survival in ...
Annika Glotzbach   +11 more
doaj   +1 more source

PPARα Agonists Inhibit Tissue Factor Expression in Human Monocytes and Macrophages [PDF]

open access: bronze, 2001
Bernadette Neve   +7 more
openalex   +1 more source

Human Factors Considerations in System Design [PDF]

open access: yes
Human factors considerations in systems design was examined. Human factors in automated command and control, in the efficiency of the human computer interface and system effectiveness are outlined.
Mitchell, C. M.   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Human Intrinsic Factor-Vitamin B12 Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region [PDF]

open access: bronze, 1998
Renata Kozyraki   +7 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The role of circadian preferred time of day and sleep pressure in tDCS-induced neuroplasticity and associated cognition

open access: yesBrain Stimulation, 2023
Mohammad Ali Salehinejad   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The Impact of sleep deprivation on cortical excitability and tDCS-induced LTP and LTD-like neuroplasticity

open access: yesBrain Stimulation, 2023
Mohammad Ali Salehinejad   +3 more
doaj   +1 more source

Somatosensory Response to Trigeminal Stimulation: A Functional Near-Infrared Spectroscopy (fNIRS) Study

open access: yesScientific Reports, 2018
Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique measuring relative hemodynamic changes in superficial cortical structures. It has successfully been applied to detect a hemodynamic response in the somatosensory cortex evoked ...
Christine I. Hucke   +3 more
doaj   +1 more source

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