Results 231 to 240 of about 10,781,581 (397)

Global variation in copy number in the human genome

Nature, 2006
R. Redon, S. Ishikawa, Karen R. Fitch, L. Feuk, L. Feuk, G. Perry, T. Andrews, H. Fiegler, M. Shapero, A. Carson, A. Carson, Wenwei Chen, Eun Kyung Cho, Stephanie Dallaire, J. Freeman, J. González, M. Gratacós, Jing Huang, Dimitrios Kalaitzopoulos, Daisuke Komura, J. MacDonald, C. Marshall, C. Marshall, R. Mei, Lyndal Montgomery, Keunihiro Nishimura, Kohji Okamura, Kohji Okamura, F. Shen, M. Somerville, J. Tchinda, A. Valsesia, Cara Woodwark, Fengtang Yang, Junjun Zhang, T. Zerjal, Jane Zhang, L. Armengol, D. Conrad, X. Estivill, X. Estivill, C. Tyler-Smith, N. Carter, H. Aburatani, Charles Lee, Charles Lee, K. W. Jones, S. Scherer, S. Scherer, M. Hurles   +49 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Papillomavirus genomes in human cervical tumors: analysis of their transcriptional activity. [PDF]

, 1985
H. Lehn, Paul A. Krieg, Gerhard Sauer
openalex   +1 more source

The Human Genome Project [PDF]

IUBMB Life, 2001
openaire   +3 more sources

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Nature Biotechnology, 2019
Daehwan Kim, Joseph M. Paggi, Chanhee Park, C. Bennett, S. Salzberg   +4 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Electrophoretic study of the genome of human rotaviruses from Rio de Janeiro, São Paulo and Pará, Brazil [PDF]

, 1983
H. G. Pereira, Rosete S. Azeredo, José Paulo G. Leite, J. A. N. Candeias, Maria Lúcia Rácz, A. C. Linhares, Yvonne B. Gabbay, J. R. Trabulsi   +7 more
openalex   +1 more source

High-Resolution Profiling of Histone Methylations in the Human Genome

Cell, 2007
A. Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Dustin E. Schones, Zhibin Wang, Gang Wei, I. Chepelev, K. Zhao   +8 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Biosemiotics, Bioinformatics, and Responsibility: Ambivalent Consequences of the Deciphering of the Human Genome for Society and Science

, 1970
Klaus Fuchs-Kittowski, Hans-Alfred Rosenthal   +1 more
openalex   +2 more sources