Results 121 to 130 of about 988,007 (335)
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Nature, 2007 E. Birney, J. Stamatoyannopoulos, A. Dutta, R. Guigó, T. Gingeras, E. Margulies, Z. Weng, M. Snyder, E. Dermitzakis, R. Thurman, Michael S. Kuehn, Christopher M. Taylor, Shane J. Neph, Christoph M. Koch, S. Asthana, A. Malhotra, I. Adzhubei, J. Greenbaum, R. Andrews, Paul Flicek, Patrick J Boyle, Hua Cao, N. Carter, Gayle K. Clelland, S. Davis, Nathan Day, P. Dhami, Shane C. Dillon, M. Dorschner, H. Fiegler, P. Giresi, Jeff Goldy, M. Hawrylycz, Andrew K. Haydock, R. Humbert, K. James, Brett E. Johnson, Ericka M. Johnson, Tristan Frum, Elizabeth R. Rosenzweig, N. Karnani, K. Lee, Gregory Lefebvre, P. Navas, Fidencio V. Neri, Stephen C. J. Parker, P. Sabo, R. Sandstrom, A. Shafer, D. Vetrie, M. Weaver, S. Wilcox, Man Yu, F. Collins, J. Dekker, J. Lieb, T. Tullius, G. Crawford, S. Sunyaev, W. S. Noble, I. Dunham, F. Denoeud, A. Reymond, P. Kapranov, J. Rozowsky, D. Zheng, R. Castelo, A. Frankish, J. Harrow, Srinka Ghosh, A. Sandelin, I. Hofacker, R. Baertsch, Damian Keefe, S. Dike, Jill Cheng, H. Hirsch, E. Sekinger, Julien Lagarde, J. F. Abril, Atif Shahab, Christoph Flamm, C. Fried, J. Hackermüller, Jana Hertel, Manja Lindemeyer, Kristin Missal, Andrea Tanzer, Stefan Washietl, J. Korbel, O. Emanuelsson, J. S. Pedersen, N. Holroyd, Ruth Taylor, D. Swarbreck, N. Matthews, M. Dickson, D. Thomas, M. Weirauch, J. Gilbert, J. Drenkow, I. Bell, X. Zhao, K. Srinivasan, W. Sung, H. Ooi, K. Chiu, S. Foissac, T. Alioto, M. Brent, L. Pachter, M. Tress, A. Valencia, S. Choo, C. Choo, C. Ucla, C. Manzano, Carine Wyss, E. Cheung, T. Clark, James B. Brown, M. Ganesh, Sandeep Patel, H. Tammana, Jacqueline Chrast, Charlotte N. Henrichsen, C. Kai, J. Kawai, Ugrappa Nagalakshmi, Jiaqian Wu, Zheng Lian, Jin Lian, P. Newburger, Xueqing Zhang, P. Bickel, J. Mattick, Piero Carninci, Y. Hayashizaki, S. Weissman, T. Hubbard, R. M. Myers, J. Rogers, P. Stadler, T. Lowe, Chia-Lin Wei, Y. Ruan, K. Struhl, M. Gerstein, S. Antonarakis, Yutao Fu, E. Green, Ulas Karaöz, A. Siepel, James Taylor, L. Liefer, K. Wetterstrand, P. Good, E. Feingold, M. Guyer, G. Cooper, G. Asimenos, Colin N. Dewey, Minmei Hou, S. Nikolaev, J. Montoya-Burgos, A. Löytynoja, S. Whelan, F. Pardi, Tim Massingham, Haiyan Huang, Na Zhang, I. Holmes, J. Mullikin, A. Ureta-Vidal, B. Paten, Michael R. Seringhaus, D. Church, K. Rosenbloom, W. Kent, Eric A. Stone, S. Batzoglou, N. Goldman, R. Hardison, D. Haussler, Webb Miller, A. Sidow, N. Trinklein, Zhengdong D. Zhang, Leah Barrera, R. Stuart, D. King, A. Ameur, Stefan Enroth, M. Bieda, Jonghwan Kim, A. Bhinge, N. Jiang, Jun Liu, Fei Yao, V. Vega, C. Lee, Patrick Ng, A. Yang, Z. Moqtaderi, Zhou Zhu, Xiaoqin Xu, S. Squazzo, M. Oberley, David Inman, Michael A. Singer, T. Richmond, Kyle J. Munn, Á. Rada-Iglesias, O. Wallerman, J. Komorowski, J. Fowler, Phillippe Couttet, Alexander W. Bruce, O. Dovey, P. Ellis, C. Langford, D. Nix, G. Euskirchen, S. Hartman, A. Urban, P. Kraus, Sara Van Calcar, Nathaniel D. Heintzman, Tae Hoon Kim, Kun Wang, Chunxu Qu, G. Hon, R. Luna, C. Glass, M. Rosenfeld, S. F. Aldred, S. Cooper, Anason S. Halees, J. M. Lin, H. Shulha, Xiaoling Zhang, Mousheng Xu, Jaafar N. Haidar, Yon-Jong Yu, V. Iyer, Roland Green, C. Wadelius, P. Farnham, B. Ren, R. Harte, A. Hinrichs, Heather Trumbower, H. Clawson, Jennifer Hillman-Jackson, A. Zweig, Kayla E. Smith, Archana Thakkapallayil, G. Barber, R. Kuhn, D. Karolchik, L. Armengol, C. Bird, P. D. de Bakker, Andrew D. Kern, N. López-Bigas, Joel D Martin, B. Stranger, A. Woodroffe, Eugene Davydov, A. Dimas, E. Eyras, Ingileif B. Hallgrímsdóttir, J. Huppert, M. Zody, G. Abecasis, X. Estivill, G. Bouffard, Xiaobin Guan, Nancy F. Hansen, J. Idol, V. Maduro, Baishali Maskeri, Jennifer C Mcdowell, Morgan Park, Pamela J. Thomas, Alice C. Young, R. Blakesley, D. Muzny, E. Sodergren, D. Wheeler, K. Worley, Huaiyang Jiang, G. Weinstock, R. Gibbs, T. Graves, R. Fulton, E. Mardis, R. Wilson, M. Clamp, James A. Cuff, S. Gnerre, D. Jaffe, Jean L. Chang, K. Lindblad-Toh, E. Lander, M. Koriabine, M. Nefedov, K. Osoegawa, Y. Yoshinaga, B. Zhu, P. D. de Jong +310 moresemanticscholar +1 more sourceIdentifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao +13 morewiley +1 more sourceCurrent trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor +6 morewiley +1 more sourceCharacterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca +11 morewiley +1 more source
