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THE recent isolation of human growth hormone from pituitary glands collected at autopsy has been of major importance in the investigation of human pituitary physiology.1 , 2 Metabolic studies have confirmed the remarkable anabolic and growth-promoting actions of this hormone in man,3 , 4 in contrast to the negative or equivocal clinical results ...
M. S. Raben
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Cadaveric Human Growth Hormone–Associated Creutzfeldt-Jakob Disease with Long Latency Period, United States [PDF]
We report a case of iatrogenic Creutzfeldt-Jakob disease (iCJD) after a 48.3-year incubation period in a patient treated with cadaveric human growth hormone.
Anatevka S. Ribeiro+9 more
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Human growth hormone is a successful treatment for children who without it would grow up to be midgets. This article describes present knowledge of its physiology, its role in the regulation of growth and its effect in treatment.
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The Molecular Properties of Human Growth Hormone
Abstract The stability of human growth hormone to acid, alkali, and urea has been evaluated by fluorescence, absorption, and circular dichroism spectroscopy. In accord with previous studies on other growth hormones and prolactins, similar molecular transitions were observed although small shifts in parameters were found among the different proteins. It
ALOJ, SALVATORE MARIA, EDELHOCH H.
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Studies with human growth hormone. [PDF]
Douglas Hubble
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STUDIES ON HUMAN GROWTH HORMONE. I. A RADIO-IMMUNOASSAY FOR HUMAN GROWTH HORMONE* [PDF]
Mary L. Parker+2 more
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Vitamin D and Parathyroid Hormone during Growth Hormone Treatment
Background. There is some controversy concerning a potential interaction between vitamin D and PTH and the GH/IGF-1 axis. The goal of this study is to assess vitamin D and PTH status in children with GH deficiency at diagnostic and during treatment with ...
Teodoro Durá-Travé+1 more
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Prader-Willi syndrome and growth hormone therapy: exploring the precise management of hypothalamic short stature: A review [PDF]
Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by various clinical features linked to hypothalamic/pituitary gland abnormalities. Growth hormone deficiency is a prominent feature of PWS that results in poor linear growth and delayed
Aram Yang
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Enhancement of The Stability of Human Growth Hormone by Using Tris(hydroxymethyl)aminomethane: Molecular Docking and Experimental Analysis [PDF]
Objective: It is so difficult to formulate human growth hormone (hGH) in a solution with high stability and new drug delivery system (NDDs) due to physiochemical instability. The purpose of this study was to investigate the possibility of using Tris as
Siyavash Mirzaei+6 more
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