Results 21 to 30 of about 1,820,127 (391)

Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]

, 2007
The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY, Halban, PA, Hou, JC, Leung, YM, Min, L, Pessin, JE, Tomas, A, Watson, RT   +7 more
core   +2 more sources

Human placental growth hormone in normal and abnormal fetal growth

Biomedical Reports, 2017
Human placental growth hormone (PGH), encoded by the growth hormone (GH) variant gene on chromosome 17, is expressed in the syncytiotrophoblast and extravillous cytotrophoblast layers of the human placenta.
Alexandros Velegrakis, Maria Sfakiotaki, S. Sifakis   +2 more
semanticscholar   +1 more source

Prolactin [PDF]

, 1977
During an oral glucose tolerance test (OGTT) glucose and insulin levels were measured in 26 patients with prolactin-producing pituitary tumours without growth hormone excess.
A. Renauld, A. Weissmann, A.C. Herrington, A.J. Lostroh, B. Winkler, C.N. Hales, E. Cerasi, E.E. McGarry, F.H. Schmidt, I.B. Rathgeb, J. Tourniaire, J.D. Manns, K. von Werder, K. Werder von, K. Werder von, M. M. C. Landgraf-Leurs, M.O. Thorner, M.W. Sinkoff, P. Berle, P. C. Scriba, R. Hörl, R. Landgraf, R. Landgraf, R.C. Bodo De, Y.N. Sinha   +24 more
core   +1 more source

Perspectives on long-acting growth hormone therapy in children and adults

Archives of Endocrinology and Metabolism, 2020
Growth hormone therapy with daily injections of recombinant human growth hormone has been available since 1985, and is shown to be safe and effective treatment for short stature in children and for adult growth hormone deficiency. In an effort to produce
Rayhan A. Lal, Andrew R. Hoffman
doaj   +1 more source

Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]

, 2018
Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng, Kommagani, Ramakrishna, Michalski, Stephanie   +2 more
core   +2 more sources

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

Italian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni, S. Motta, N. Masera, S. Gasperini, A. Rovelli, R. Parini   +5 more
doaj   +1 more source

High Sensitivity Mass Spectrometric Quantification of Serum Growth Hormone by Amphiphilic Peptide Conjugation [PDF]

, 2012
Amphiphilic peptide conjugation affords a significant increase in sensitivity with protein quantification by electrospray-ionization mass spectrometry.
Arsene, Arsene, Barkan, Busch, Cech, Cech, Chai, Chanson, Foettinger, Frahm, Giustina, Halquist, Hofmann, Kulevich, Ligon, Litterscheid, Markkanen, Mirzaei, Shortreed, Shuford, Ullmer, Williams, Williams, Wu, Yang, Yang   +25 more
core   +1 more source

Differential Tissue Response to Growth Hormone in Mice [PDF]

, 2018
Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R., Berry, Ryan, Frank, Stuart J., McGinnis, Graham R., Young, Martin E.   +4 more
core   +2 more sources

Short Stature in children: Review Article

SVU - International Journal of Medical Sciences, 2023
Background: Humans' final adult height is influenced by a variety of factors. A common paediatric endocrine issue, short stature has a variety of reasons, but normal variations account for the majority of cases.
Ahmed El-Abd Ahmed, Mohammed H Hassan, Renada Saad Hamdan, Hala M. Sakhr   +3 more
doaj   +1 more source

Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]

, 2016
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
Ahmed, S.F., Ahmid, M., Perry, C.G., Shaikh, M.G.   +3 more
core   +2 more sources