Results 111 to 120 of about 923,221 (312)

Cooking shapes the structure and function of the gut microbiome [PDF]

, 2019
Diet is a critical determinant of variation in gut microbial structure and function, outweighing even host genetics1-3. Numerous microbiome studies have compared diets with divergent ingredients1-5, but the everyday practice of cooking remains ...
Turnbaugh, Peter
core  

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

metaGEM: Human gut dataset

, 2021
Results from human_gut dataset generated for metaGEM paper. Please consider citing the original metaGEM publication if you use these models in your research.
openaire   +1 more source

Noncontiguous finished genome sequence and description of Virgibacillus massiliensis sp. nov., a moderately halophilic bacterium isolated from human gut

New Microbes and New Infections, 2015
Strain Vm-5T was isolated from the stool specimen of a 10-year-old Amazonian boy. This bacterium is a Gram-positive, strictly aerobic rod, motile by a polar flagellum. Here we describe its phenotypic characteristics and complete genome sequence.
S. Khelaifia, O. Croce, J.-C. Lagier, C. Robert, C. Couderc, F. Di Pinto, B. Davoust, F. Djossou, D. Raoult, P.-E. Fournier   +9 more
doaj   +1 more source

Hypoxia Inducible Factor-1α: The Curator of Gut Homeostasis

Frontiers in Cellular and Infection Microbiology, 2020
The human gut microbiome is a stratified and resilient ecosystem co-inhabited by a diverse and dynamic pool of microorganisms. Microbial selection, establishment, and colonization are modulated through a complex molecular network of host-microbial ...
Tarun Kumar, Rajesh Pandey, Nar Singh Chauhan   +2 more
doaj   +1 more source

GABA-modulating bacteria of the human gut microbiota. [PDF]

, 2019
The gut microbiota affects many important host functions, including the immune response and the nervous system1. However, while substantial progress has been made in growing diverse microorganisms of the microbiota2, 23-65% of species residing in the ...
Clardy, Jon, Dietrich, David, Dubin, Marc J, Gilbert, Jack A, Kim, Ki Hyun, Knight, Rob, Lekbua, Asama, Levering, Jennifer, Lewis, Kim, Liston, Conor, Liu, Joanne K, McDonald, Daniel, Mroue, Nader, Ramadhar, Timothy R, Sharma, Anukriti, Stewart, Eric J, Strandwitz, Philip, Terekhova, Darya, Zengler, Karsten   +18 more
core  

Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]

, 2018
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher, Burnham, Carey-Ann D, CDC Prevention Epicenter Program,, Dantas, Gautam, Dubberke, Erik R, Hink, Tiffany, Jones, Susan, Kwon, Jennie H, Langdon, Amy, Patel, Sanket, Reske, Kimberly A, Seiler, Sondra, Sun, Xiaoqing, Wallace, Meghan   +13 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Antibiotic Resistance Gene Diversity and Virulence Gene Diversity Are Correlated in Human Gut and Environmental Microbiomes

mSphere, 2019
Human beings have used large amounts of antibiotics, not only in medical contexts but also, for example, as growth factors in agriculture and livestock, resulting in the contamination of the environment.
Pedro Escudeiro, Joël Pothier, Francisco Dionisio, Teresa Nogueira   +3 more
doaj   +1 more source