Results 41 to 50 of about 923,221 (312)

Comparative genomics and phenotypic studies to determine site-specificity of Escherichia coli in the lower gastrointestinal tract of humans

Gut Microbes, 2023
Escherichia coli (E. coli) is an important commensal in the human gut; however, it is unknown whether strains show site-specificity in the lower gut. To investigate this, we assessed genotypic and phenotypic differences in 37 clone pairs (two strains ...
Rasel Barua, Paul Pavli, David M Gordon, Claire L O’Brien   +3 more
doaj   +1 more source

Human Skin, Oral, and Gut Microbiomes Predict Chronological Age. [PDF]

, 2020
Human gut microbiomes are known to change with age, yet the relative value of human microbiomes across the body as predictors of age, and prediction robustness across populations is unknown. In this study, we tested the ability of the oral, gut, and skin
Allaband, Celeste, Belda-Ferre, Pedro, Carrieri, Anna-Paola, Haiminen, Niina, Hu, Rebecca, Huang, Shi, Jiang, Lingjing, Kim, Ho-Cheol, Knight, Rob, Parida, Laxmi, Russell, Baylee, Swafford, Austin D, Vázquez-Baeza, Yoshiki, Xu, Zhenjiang Zech, Zarrinpar, Amir, Zhou, Hongwei   +15 more
core   +2 more sources

Advancing human gut microbiota research by considering gut transit time [PDF]

Gut, 2022
Accumulating evidence indicates that gut transit time is a key factor in shaping the gut microbiota composition and activity, which are linked to human health. Both population-wide and small-scale studies have identified transit time as a top covariate contributing to the large interindividual variation in the faecal microbiota composition.
Prochazkova, Nicola, Falony, Gwen, Dragsted, Lars Ove, Licht, Tine Rask, Raes, Jeroen, Roager, Henrik M.   +5 more
openaire   +5 more sources

Intestinal Metagenomes and Metabolomes in Healthy Young Males: Inactivity and Hypoxia Generated Negative Physiological Symptoms Precede Microbial Dysbiosis

Frontiers in Physiology, 2018
We explored the metagenomic, metabolomic and trace metal makeup of intestinal microbiota and environment in healthy male participants during the run-in (5 day) and the following three 21-day interventions: normoxic bedrest (NBR), hypoxic bedrest (HBR ...
Robert Šket, Tadej Debevec, Tadej Debevec, Susanne Kublik, Michael Schloter, Anne Schoeller, Boštjan Murovec, Katarina Vogel Mikuš, Damjan Makuc, Klemen Pečnik, Janez Plavec, Igor B. Mekjavić, Ola Eiken, Zala Prevoršek, Blaž Stres, Blaž Stres   +15 more
doaj   +1 more source

The Perfect Condition for the Rising of Superbugs: Person-to-Person Contact and Antibiotic Use Are the Key Factors Responsible for the Positive Correlation between Antibiotic Resistance Gene Diversity and Virulence Gene Diversity in Human Metagenomes

Antibiotics, 2021
Human metagenomes with a high diversity of virulence genes tend to have a high diversity of antibiotic-resistance genes and vice-versa. To understand this positive correlation, we simulated the transfer of these genes and bacterial pathogens in a ...
Célia P. F. Domingues, João S. Rebelo, Joël Pothier, Francisca Monteiro, Teresa Nogueira, Francisco Dionisio   +5 more
doaj   +1 more source

Microfluidic Gut-on-a-Chip: Fundamentals and Challenges

Biosensors, 2023
The human gut is responsible for food digestion and absorption. Recently, growing evidence has shown its vital role in the proper functioning of other organs.
Dimple Palanilkunnathil Thomas, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta   +3 more
doaj   +1 more source

Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain [PDF]

, 2017
BACKGROUND: Cross-sectional studies suggest that the microbes in the human gut have a role in obesity by influencing the human body's ability to extract and store calories.
A.M. Valdes, C. Menni, C.J. Steves, M.A. Jackson, T. Pallister, T.D. Spector   +5 more
core   +3 more sources

Resistant starches from dietary pulses improve neurocognitive health via gut-microbiome-brain axis in aged mice

Frontiers in Nutrition
IntroductionCognitive decline is a common consequence of aging. Dietary patterns that lack fibers and are high in saturated fats worsen cognitive impairment by triggering pro-inflammatory pathways and metabolic dysfunctions.
Saurabh Kadyan, Gwoncheol Park, Nathaniel Hochuli, Katelyn Miller, Bo Wang, Ravinder Nagpal   +5 more
doaj   +1 more source

Taxonomic Features and Comparison of the Gut Microbiome from Two Edible Fungus-Farming Termites (Macrotermes falciger, M. natalensis) Harvested in the Vhembe District of Limpopo, South Africa [PDF]

, 2019
Background Termites are an important food resource for many human populations around the world, and are a good supply of nutrients. The fungus-farming ‘higher’ termite members of Macrotermitinae are also consumed by modern great apes and are implicated ...
Duncan, Frances D., Hofman, Courney A., Honap, Tanvi P., Lesnik, Julie, Lewis, Cecil M., Netschifhefhe, Shandukani R., Schnorr, Stephanie L.   +6 more
core   +2 more sources

Extensive inter-domain lateral gene transfer in the evolution of the human commensal Methanosphaera stadtmanae

Frontiers in Genetics, 2012
Methanosphaera stadtmanae is a commensal methanogenic archaeon found in the human gut. As most of its niche-neighbors are bacteria, it is expected that lateral gene transfer (LGT) from bacteria might have contributed to the evolutionary history of this ...
Mor Nadia Lurie-Weinberger, Michael ePeeri, Tamir eTuller, Uri eGophna   +3 more
doaj   +1 more source