Results 31 to 40 of about 8,146,953 (237)

Characterization of a phospholipid‐regulated β‐galactosidase from Akkermansia muciniphila involved in mucin degradation

MicrobiologyOpen, 2019
The gut microbe Akkermansia muciniphila is important for the human health as the occurrence of the organism is inversely correlated with different metabolic disorders. The metabolism of the organism includes the degradation of intestinal mucins.
Konrad Kosciow, Uwe Deppenmeier
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Scientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng   +10 more
doaj   +1 more source

Genome sequence and description of Anaeromassilibacillus senegalensis gen. nov., sp. nov., isolated from the gut of patient with kwashiorkor

New Microbes and New Infections, 2017
Using the culturomics strategy, a wide range of anaerobic bacteria was discovered including Anaeromassilibacillus senegalensis strain mt9T (= CSUR P1511=DSM 102954), isolated from the gut microbiota of a 1-year-old Senegalese patient with kwashiorkor ...
E. Guilhot, M.T. Alou, J.-C. Lagier, N. Labas, C. Couderc, J. Delerce, A. Diallo, C. Sokhna, P.-E. Fournier, D. Raoult, S. Khelaifia   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Analyzing resistome in soil and Human gut: a study on the characterization and risk evaluation of antimicrobial peptide resistance

Frontiers in Microbiology
ObjectiveThe limited existing knowledge regarding resistance to antimicrobial peptides (AMPs) is hindering their broad utilization. The aim of this study is to enhance the understanding of AMP resistance, a pivotal factor in the exploration of ...
Chongyi Zhao, Shuo Yan, Ying Luo, Yuzhu Song, Xueshan Xia   +4 more
doaj   +1 more source

‘Pseudoflavonifractor phocaeensis’ gen. nov., sp. nov., isolated from human left colon

New Microbes and New Infections, 2017
We describe here characteristics of ‘Pseudoflavonifractor phocaeensis’ strain Marseille-P3064T, which was isolated from a human left colon wash sample.
D. Ricaboni, M. Mailhe, A. Benezech, C. Andrieu, P.-E. Fournier, D. Raoult   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

‘Acidaminococcus timonensis’ sp. nov. and ‘Acidaminococcus massiliensis’ sp. nov. isolated from human gut

New Microbes and New Infections, 2017
We report here the main characteristics of ‘Acidaminococcus timonensis’ strain Marseille-P2764T, isolated from human right colon, and ‘Acidaminococcus massiliensis’ strain Marseille-P2828T, isolated from human duodenum.
D. Ricaboni, M. Mailhe, A. Benezech, F. Cadoret, P.-E. Fournier, D. Raoult   +5 more
doaj   +1 more source