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The Human Gut Phageome: Origins and Roles in the Human Gut Microbiome [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The investigation of the microbial populations of the human body, known as the microbiome, has led to a revolutionary field of science, and understanding of its impacts on human development and health. The majority of microbiome research to date has focussed on bacteria and other kingdoms of life, such as fungi.
Eleanor M. Townsend   +6 more
openaire   +4 more sources

Healthy human gut phageome [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
Significance Humans need a stable, balanced gut microbiome (GM) to be healthy. The GM is influenced by bacteriophages that infect bacterial hosts. In this work, bacteriophages associated with the GM of healthy individuals were analyzed, and a healthy gut phageome (HGP) was discovered.
Manrique, Pilar   +5 more
openaire   +4 more sources

Shining Light on Human Gut Bacteriophages [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The human gut is a complex environment that contains a multitude of microorganisms that are collectively termed the microbiome. Multiple factors have a role to play in driving the composition of human gut bacterial communities either toward homeostasis or the instability that is associated with many disease states.
Emma Guerin   +3 more
openaire   +4 more sources

Human Gut Flora

open access: yesAmerican Journal of Surgical Case Reports, 2020
Background: The intestinal microflora is a complex ecosystem. An improved understanding of this hidden organ will reveal secrets that are relevant to human health and to several infectious, inflammatory and neoplastic disease processes. Given the ability of the immune response to rapidly counter infectious agents, it is striking that such a large ...
Abhijit Powar   +3 more
openaire   +1 more source

The Sporobiota of the Human Gut [PDF]

open access: yesGut Microbes, 2021
The human gut microbiome is a diverse and complex ecosystem that plays a critical role in health and disease. The composition of the gut microbiome has been well studied across all stages of life. In recent years, studies have investigated the production of endospores by specific members of the gut microbiome. An endospore is a tough, dormant structure
Muireann Egan   +4 more
openaire   +4 more sources

Human distal gut microbiome [PDF]

open access: yesEnvironmental Microbiology, 2011
Summary The distal gut and its associated microbiota is a new frontier in the quest to understand human biology and evolution. The renaissance in this field has been partly driven by advances in sequencing technology and also by the application of a variety of ‘omic’ technologies in a systems biology framework. In
openaire   +2 more sources

Repertoire of human gut microbes [PDF]

open access: yesMicrobial Pathogenesis, 2017
In 1675, Antoni Van Leeuwenhoeck was the first to observe several forms using an optical microscope that he named "animalcules", realizing later that these were microorganisms. The first classification of living organisms proposed by Ehrenberg in 1833 was based on what we could visualize.
Hugon, Perrine   +4 more
openaire   +2 more sources

The human gut resistome [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain.
openaire   +2 more sources

Altered distribution of mucosal NK cells during HIV infection. [PDF]

open access: yes, 2012
The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s ...
Alter, G   +13 more
core   +2 more sources

Metagenomic Characterization of the Human Intestinal Microbiota in Fecal Samples from STEC-Infected Patients

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The human intestinal microbiota is a homeostatic ecosystem with a remarkable impact on human health and the disruption of this equilibrium leads to an increased susceptibility to infection by numerous pathogens. In this study, we used shotgun metagenomic
Federica Gigliucci   +13 more
doaj   +1 more source

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