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Codiversification of gut microbiota with humans [PDF]

open access: yesScience, 2021
The gut microbiomes of human populations worldwide have many core microbial species in common. However, within a species, some strains can show remarkable population specificity. The question is whether such specificity arises from a shared evolutionary history (codiversification) between humans and their microbes. To test for codiversification of host
Taichi A. Suzuki   +24 more
openaire   +4 more sources

Human Gut Microbiota: Repertoire and Variations [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
The composition of human gut microbiota and their relationship with the host and, consequently, with human health and disease, presents several challenges to microbiologists. Originally dominated by culture-dependent methods for exploring this ecosystem, the advent of molecular tools has revolutionized our ability to investigate these relationships ...
Lagier, J. C.   +4 more
openaire   +4 more sources

Introduction to the human gut microbiota [PDF]

open access: yesBiochemical Journal, 2017
The human gastrointestinal (GI) tract harbours a complex and dynamic population of microorganisms, the gut microbiota, which exert a marked influence on the host during homeostasis and disease. Multiple factors contribute to the establishment of the human gut microbiota during infancy.
Thursby, Elizabeth, Juge, Nathalie
openaire   +2 more sources

Human Gut Microbiota and Drug Metabolism

open access: yesMicrobial Ecology, 2022
The efficacy of drugs widely varies in individuals, and the gut microbiota plays an important role in this variability. The commensal microbiota living in the human gut encodes several enzymes that chemically modify systemic and orally administered drugs, and such modifications can lead to activation, inactivation, toxification, altered stability, poor
Archana Pant   +3 more
openaire   +2 more sources

Linking gut microbiota with human diseases [PDF]

open access: yesBioinformation, 2020
The human gut is rich in microbes. Therefore, it is of interest to document data to link known human diseases with the gut microbiota. Various factors like hormones, metabolites and dietary habitats are responsible for shaping the microbiota of the gut.
Vandana, Udaya Kumar   +7 more
openaire   +2 more sources

Human seroreactivity to gut microbiota antigens [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2015
Although immune responses directed against antigens from the intestinal microbiota are observed in certain diseases, the normal human adaptive immune response to intestinal microbiota is poorly defined.Our goal was to assess the adaptive immune response to the intestinal microbiota present in 143 healthy adults and compare this response with the ...
Christmann, Benjamin S.   +8 more
openaire   +3 more sources

Gut microbiota dependant trimethylamine N-oxide and hypertension

open access: yesFrontiers in Physiology, 2023
The human gut microbiota environment is constantly changing and some specific changes influence the host’s metabolic, immune, and neuroendocrine functions.
Katongo H. Mutengo   +6 more
doaj   +1 more source

Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]

open access: yes, 2015
BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R.   +13 more
core   +5 more sources

The Relationship Between Breast Milk Components and the Infant Gut Microbiota

open access: yesFrontiers in Nutrition, 2021
The assembly of the newborn's gut microbiota during the first months of life is an orchestrated process resulting in specialized microbial ecosystems in the different gut compartments. This process is highly dependent upon environmental factors, and many
Gaëlle Boudry   +8 more
doaj   +1 more source

Impact of the gut microbiota on inflammation, obesity, and metabolic disease [PDF]

open access: yes, 2016
The human gut harbors more than 100 trillion microbial cells, which have an essential role in human metabolic regulation via their symbiotic interactions with the host.
Boulangé, CL   +4 more
core   +1 more source

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