Results 31 to 40 of about 176,456 (164)

Gut-Brain Psychology: Rethinking Psychology From the Microbiota–Gut–Brain Axis

Frontiers in Integrative Neuroscience, 2018
Mental disorders and neurological diseases are becoming a rapidly increasing medical burden. Although extensive studies have been conducted, the progress in developing effective therapies for these diseases has still been slow.
Shan Liang, Xiaoli Wu, Xiaoli Wu, Feng Jin   +3 more
doaj   +1 more source

Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity

Molecules, 2021
Probiotics are beneficial active microorganisms that colonize the human intestines and change the composition of the flora in particular parts of the host. Recently, the use of probiotics to regulate intestinal flora to improve host immunity has received
Xinzhou Wang, Peng Zhang, Xin Zhang
doaj   +1 more source

Biological Aging and the Human Gut Microbiota [PDF]

The Journals of Gerontology: Series A, 2017
The human gastrointestinal microbiota plays a key homeostatic role in normal functioning of physiologic processes commonly undermined by aging. We used a previously validated 34-item frailty index (FI34) to identify changes in gut microbiota community structure associated with biological age of community-dwelling adults.
Vincent J, Maffei, Sangkyu, Kim, Eugene, Blanchard, Meng, Luo, S Michal, Jazwinski, Christopher M, Taylor, David A, Welsh   +6 more
openaire   +2 more sources

The gut microbiota and diabetic cardiomyopathy in humans

Diabetes & Metabolism, 2020
Type 2 diabetes (DT2) increases the risk of cardiovascular events and cardiac insufficiency. This insufficiency is mostly post-ischaemic in nature, but other aetiologies are possible in this high-risk population. In patients with DT2, diabetic cardiomyopathy is a recognized cause of cardiac insufficiency secondary to chronic hyperglycaemia and ...
Bastin, M., Andreelli, F.
openaire   +3 more sources

Towards a safer probiotic: clbD deletion attenuates EcN-induced DNA damage responses and epithelial inflammatory transcriptional responses

Frontiers in Cellular and Infection Microbiology
Escherichia coli Nissle 1917 (EcN) is widely used as a probiotic and engineering chassis, but its carriage of the pks genomic island raises safety concerns related to the genotoxin colibactin.
Wei-Ming Chen, Wei-Ming Chen, Wei-Ming Chen, Ming-Yang Sun, Ming-Yang Sun, Ming-Yang Sun, Ji-Yuan Ye, Ji-Yuan Ye, Ji-Yuan Ye, De-Cheng Tan, De-Cheng Tan, De-Cheng Tan, Zi-Yi Zhang, Zi-Yi Zhang, Zi-Yi Zhang, Jing-Jing Liu, Jing-Jing Liu   +16 more
doaj   +1 more source

Influence of Mediterranean Diet on Human Gut Microbiota [PDF]

Nutrients, 2020
Gut microbiota changes correlate with health status. Literature data on gut microbiota show that all dietary changes can induce the alteration of gut microbiota composition. Mediterranean diet (MD) is associated with a reduction of all-cause mortality and in this review, we analyzed its interactions with human microbiota. In particular, we explored the
Giuseppe Merra, Annalisa Noce, Giulia Marrone, Marco Cintoni, Maria Grazia Tarsitano, Annunziata Capacci, Antonino De Lorenzo   +6 more
openaire   +3 more sources

Association between serum total cholesterol levels and Crohn’s clinical disease severity: a retrospective cross-sectional study

Frontiers in Medicine
BackgroundThis retrospective cross-sectional study aimed to investigate the relationship between serum total cholesterol (TC) levels and the clinical activity of Crohn’s disease (CD).MethodsOne hundred and four patients with Crohn’s disease (CD) and ...
Jinchun Ni, Yunna Tang, Fangyuan Zhou, Fangyuan Zhou, Fangyuan Zhou, Yiqun Hu, Lupeng Liu, Mingcheng Huang, Hui Ouyang, Chenxi Xie, Chenxi Xie, Chenxi Xie   +11 more
doaj   +1 more source

Specificities of chemosensory receptors in the human gut microbiota. [PDF]

Proc Natl Acad Sci U S A
Abstract The human gut is rich in metabolites and harbors a complex microbial community, yet the sensory repertoire of its commensal bacteria remains largely uncharacterized. Here we systematically mapped ligand specificities of extracytoplasmic sensory domains from twenty members of the human gut microbiota, with a primary focus on the
Xu W, Jalomo-Khayrova E, Gumerov VM, Ross PA, Köbel TS, Schindler D, Bange G, Zhulin IB, Sourjik V.   +8 more
europepmc   +6 more sources

The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Scientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng   +10 more
doaj   +1 more source

The gut-brain axis in ischemic stroke: its relevance in pathology and as a therapeutic target

Neurological Research and Practice, 2022
The gut contains the largest reservoir of microorganisms of the human body, termed as the gut microbiota which emerges as a key pathophysiological factor in health and disease. The gut microbiota has been demonstrated to influence various brain functions
Corinne Benakis, Arthur Liesz
doaj   +1 more source