The gut virome and human health: From diversity to personalized medicine
Engineering MicrobiologyThe human gut virome plays a crucial role in the gut and overall health; its diversity and regulatory functions influence bacterial populations, metabolism, and immune responses.
Rahul Harikumar Lathakumari +6 more
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Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome? [PDF]
Mediators of Inflammation, 2015 The human virome comprises viruses that infect host cells, virus-derived elements in our chromosomes, and viruses that infect other organisms, including bacteriophages and plant viruses.
Alfredo Focà +5 more
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Metagenomic analysis of the human gut virome reveals functional signatures and viral stability across hospitalized and non-hospitalized diarrheal and non-diarrheal individuals [PDF]
Gut PathogensBackground The human gut virome is a fundamental yet understudied component of the intestinal microbiome. However, its taxonomic composition and functional potential in Latin American populations remain poorly understood, particularly under clinical ...
Angie L. Ramírez +8 more
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Machine learning and causal inference applied to the gut metagenome-metabolome axis reveals a link between neonatal jaundice and autism spectrum disorder [PDF]
mSystemsNeonatal jaundice (NJ) might increase the risk of autism spectrum disorder (ASD) in children. This study examined whether alterations in the gut microbiota could explain the link between NJ and ASD.
Xianhong Chen +12 more
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Characterization of the human gut virome in metabolic and autoimmune diseases. [PDF]
Inflamm Regen, 2022 AbstractThe intestinal microbiome is dominated by bacteria and plays a pivotal role in the occurrence and development of disease, including several metabolic and autoimmune disorders. While intestinal viral communities, primarily made up of bacteriophages, are also thought to play a role in disease pathogenesis in the gastrointestinal tract, they have ...
Fujimoto K, Miyaoka D, Uematsu S.
europepmc +4 more sources
Nature CommunicationsFresh vegetables harbor diverse microorganisms on leaf surfaces, yet their viral communities remain unexplored. We investigate the diversity and ecology of phyllosphere viromes of six leafy green vegetables using virus-like particle (VLP) enrichment and ...
Ji-Woo Park +6 more
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The Human Gut Virome and Its Relationship with Nontransmissible Chronic Diseases. [PDF]
Nutrients, 2023 The human gastrointestinal tract contains large communities of microorganisms that are in constant interaction with the host, playing an essential role in the regulation of several metabolic processes. Among the gut microbial communities, the gut bacteriome has been most widely studied in recent decades.
Ezzatpour S +6 more
europepmc +3 more sources
Dysbiosis of fecal virome in pediatric Crohn’s disease and its dynamic changes during infliximab therapy [PDF]
mSystemsThe gut virome is an emerging but underexplored component of the human microbiota, especially in pediatric Crohn’s disease (CD). This study aimed to characterize the fecal virome in children with CD and evaluate its association with clinical response to ...
Ting Ge +14 more
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Impact of phage enrichment on the observed infant gut phageome [PDF]
Microbiology SpectrumThe human gut microbiota, particularly during infancy, plays a pivotal role in shaping long-term health outcomes. While research on the bacterial microbiota has advanced rapidly, the infant gut virome—dominated by bacteriophages—remains underexplored due
Sandro Valenzuela-Diaz +7 more
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Community Types of the Human Gut Virome are Associated with Endoscopic Outcome in Ulcerative Colitis. [PDF]
J Crohns Colitis, 2023 Abstract Background Inflammatory bowel disease [IBD] is a major debilitating disease. Recently, the gut microbiota has gained attention as an important factor involved in the pathophysiology of IBD.
Jansen D +9 more
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