Results 51 to 60 of about 78,351 (172)

Stability of the human gut virome and effect of gluten-free diet.

Cell Reports, 2020
The human gut microbiome consists of bacteria, archaea, eukaryotes, and viruses. The gut viruses are relatively underexplored. Here, we longitudinally analyzed the gut virome composition in 11 healthy adults: its stability, variation, and the effect of a
S. Garmaeva, Anastasia A. Gulyaeva, T. Sinha, A. Shkoporov, Adam G. Clooney, S. Stockdale, Johanne E. Spreckels, T. Sutton, L. Draper, B. Dutilh, C. Wijmenga, A. Kurilshikov, Jingyuan Fu, C. Hill, A. Zhernakova   +14 more
semanticscholar   +1 more source

A loss of crAssphage stability in the human gut virome is associated with obesity and metabolic syndrome

bioRxiv, 2022
Viral metagenomics studies of the human gut microbiota unravel differences in phage populations between healthy and disease, stimulating interest in the role that phages play in bacterial ecosystem regulation.
Melany Cervantes-Echeverría, Luigui Gallardo-Becerra, F. Cornejo-Granados, Adrian Ochoa Leyva   +3 more
semanticscholar   +1 more source

Human Virome and Disease: High-Throughput Sequencing for Virus Discovery, Identification of Phage-Bacteria Dysbiosis and Development of Therapeutic Approaches with Emphasis on the Human Gut

Viruses, 2019
The virome is comprised of endogenous retroviruses, eukaryotic viruses, and bacteriophages and is increasingly being recognized as an essential part of the human microbiome. The human virome is associated with Type-1 diabetes (T1D), Type-2 diabetes (T2D),
Tasha M. Santiago-Rodriguez, Emily B. Hollister   +1 more
doaj   +1 more source

Impact of HIV infection and integrase strand transfer inhibitors-based treatment on the gut virome

Scientific Reports, 2022
Viruses are the most abundant components of the human gut microbiome with a significant impact on health and disease. The effects of human immunodeficiency virus (HIV) infection on gut virome has been scarcely analysed.
Pablo Villoslada-Blanco, Patricia Pérez-Matute, María Íñiguez, Emma Recio-Fernández, Daan Jansen, Lander De Coninck, Lila Close, Pilar Blanco-Navarrete, Luis Metola, Valvanera Ibarra, Jorge Alba, Jelle Matthijnssens, José A. Oteo   +12 more
doaj   +1 more source

Gut dsDNA virome shows diversity and richness alterations associated with childhood obesity and metabolic syndrome

iScience, 2021
Summary: Changes in the human gut microbiome are associated with obesity and metabolic syndrome, but the role of the gut virome in both diseases remains largely unknown. We characterized the gut dsDNA virome of 28 school-aged children with healthy normal-
Shirley Bikel, Gamaliel López-Leal, Fernanda Cornejo-Granados, Luigui Gallardo-Becerra, Rodrigo García-López, Filiberto Sánchez, Edgar Equihua-Medina, Juan Pablo Ochoa-Romo, Blanca Estela López-Contreras, Samuel Canizales-Quinteros, Abigail Hernández-Reyna, Alfredo Mendoza-Vargas, Adrian Ochoa-Leyva   +12 more
doaj   +1 more source

Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity

Microbiome, 2021
Background Coronavirus disease 2019 (COVID-19) caused by the enveloped RNA virus SARS-CoV-2 primarily affects the respiratory and gastrointestinal tracts.
Tao Zuo, Qin Liu, Fen Zhang, Yun Kit Yeoh, Yating Wan, Hui Zhan, Grace C. Y. Lui, Zigui Chen, Amy Y. L. Li, Chun Pan Cheung, Nan Chen, Wenqi Lv, Rita W. Y. Ng, Eugene Y. K. Tso, Kitty S. C. Fung, Veronica Chan, Lowell Ling, Gavin Joynt, David S. C. Hui, Francis K. L. Chan, Paul K. S. Chan, Siew C. Ng   +21 more
doaj   +1 more source

Human virome: Implications in cancer

Heliyon, 2023
In recent years, the human virome has gained importance, especially after the SARS-CoV-2 pandemic, due to its possible involvement in autoimmune, inflammatory diseases, and cancer.
Rafael Tamayo-Trujillo, Patricia Guevara-Ramírez, Santiago Cadena-Ullauri, Elius Paz-Cruz, Viviana A. Ruiz-Pozo, Ana Karina Zambrano   +5 more
doaj   +1 more source

Metagenomic analysis reveals unexplored diversity of archaeal virome in the human gut

Nature Communications, 2022
Abstract The human gut microbiome has been extensively explored, while the archaeal viruses remain largely unknown. Here, we present a comprehensive analysis of the archaeal viruses from the human gut metagenomes and the existing virus collections using the CRISPR spacer and viral signature-based approach.
Ran Li, Yongming Wang, Han Hu, Yan Tan, Yingfei Ma   +4 more
openaire   +3 more sources

Characterizing Enterotypes in Human Metagenomics: A Viral Perspective

Frontiers in Microbiology, 2021
The diversity and high genomic mutation rates of viral species hinder our understanding of viruses and their contributions to human health. Viral enterotypes as a description of the gut virome, its characteristics have not been thoroughly studied.
Li Song, Lu Zhang, Xiaodong Fang
doaj   +1 more source

Short Communication: Obesity Intervention Resulting in Significant Changes in the Human Gut Viral Composition

Applied Sciences, 2021
Obesity is a health problem of global concern that negatively impacts quality of life. Various studies have implicated obesity in the disruption of the normal microbiome composition.
Diego Sandoval-Vargas, Nataly D. Concha-Rubio, Paola Navarrete, Matías Castro, Daniel A. Medina   +4 more
doaj   +1 more source