Results 81 to 90 of about 78,351 (172)

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Discordant transmission of bacteria and viruses from mothers to babies at birth

Microbiome, 2019
Background The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Rabia Maqsood, Rachel Rodgers, Cynthia Rodriguez, Scott A. Handley, I. Malick Ndao, Phillip I. Tarr, Barbara B. Warner, Efrem S. Lim, Lori R. Holtz   +8 more
doaj   +1 more source

Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis

Microbiome, 2022
Background Inflammatory bowel diseases (IBDs) including Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by chronic and debilitating gut inflammation.
Anshul Sinha, Yue Li, Mohammadali Khan Mirzaei, Michael Shamash, Rana Samadfam, Irah L. King, Corinne F. Maurice   +6 more
doaj   +1 more source

Gut Microbiome Dysbiosis is Associated With Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Infection and Disease Progression to HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis: A Cross‐Sectional Study

Smart Medicine, Volume 5, Issue 1, February 2026.
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes, Ana Olivia de Souza, Youko Nukui, Rosa Maria Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Patricia Bianca Clissa, Silas G. Villas‐Boas, Sabri Saeed Sanabani   +8 more
wiley   +1 more source

The Revival of the Battle between David and Goliath in the Enteric Viruses and Microbiota Struggle: Potential Implication for Celiac Disease

Microorganisms, 2019
The human gut is inhabited by overcrowded prokaryotic communities, a major component of which is the virome, comprised of viruses, bacteriophages, archaea, eukaryotes and bacteria.
Aaron Lerner, Ajay Ramesh, Torsten Matthias   +2 more
doaj   +1 more source

The microbiota–gut–brain axis in mild cognitive impairment and Alzheimer's disease: a scoping review of human studies

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Alzheimer's disease (AD) is projected to become the highest‐burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut microbiomes in mild cognitive impairment (MCI) and AD included dietary and probiotic interventions.
Alison Warren, Zan Wynia, Patrick G. Corr, Mershad Fahim Devin, Zeynep Celikkol, Lindsey Gordon, Mina Farah, Michaela Karam, Daniel Villarreal, Scott A. Jackson, Leigh A. Frame   +10 more
wiley   +1 more source

The emerging role of the gut virome in necrotizing enterocolitis

Heliyon
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates, particularly preterm infants. Many factors can lead to NEC, but microbial dysbiosis is one of the most important risk factors that can induce this disease.
Cong Yi, Jia Chen, Xiang She
doaj   +1 more source

Editorial: Gut virome and human health

Frontiers in Cellular and Infection Microbiology, 2022
Yuan Gao, Michael B. Sohn, Jinfeng Wang
openaire   +3 more sources

The Microbiome Within a Microbe: Rethinking Blastocystis Biology

Journal of Eukaryotic Microbiology, Volume 73, Issue 1, January/February 2026.
ABSTRACT Blastocystis spp., one of the most prevalent microeukaryotes in the human gut, has long puzzled researchers with its ambiguous role in health and disease. Decades‐old microscopy studies reported bacterial‐ and viral‐like particles within Blastocystis spp. cells, but these findings have been mainly overlooked.
Daisy Shaw, Eleni Gentekaki, Anastasios D. Tsaousis   +2 more
wiley   +1 more source

Molecular and Functional Insights Into the Avian Gut Microbiota: Roles in Health, Disease Resistance, and Microbiome Modulation

Advanced Gut &Microbiome Research, Volume 2026, Issue 1, 2026.
The avian gut microbiota constitutes a complex, multiphyla ecosystem that critically shapes host physiology, immune function, disease resistance, and antimicrobial resistance dynamics. Bacteria, archaea, fungi, and viruses collectively regulate nutrient metabolism, mucosal barrier integrity, and immunological maturation, whereas dysbiosis increases ...
Adetolase Azizat Bakre, Ridwan Olamilekan Adesola, Ibrahim Idris, Jian Wu   +3 more
wiley   +1 more source