Results 101 to 110 of about 8,383,878 (290)
Persistent infection of a human lymphoblastoid cell line with equine herpesvirus 1 [PDF]
L F Roumillat+2 more
openalex +1 more source
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie+9 more
wiley +1 more source
Background/Objectives: Ulcerative colitis (UC) and Crohn’s disease (CD) are the usual clinical forms of inflammatory bowel disease (IBD). Changes in the oral microbiota, especially the presence of emerging fungi and herpesviruses, have been shown to ...
Manoel Marques Evangelista Oliveira+11 more
doaj +1 more source
Human Herpesvirus Infections. Clinical Aspects [PDF]
Mark Wansbrough‐Jones
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Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall+6 more
wiley +1 more source
Molecular Mechanisms of Cell-to-Cell Transmission in Human Herpesviruses
Members of the family Orthoherpesviridae employs two distinct transmission modes: free virion release and cell-to-cell transmission. The latter enables immune evasion through multiple mechanisms, facilitating infections in skin, mucosa, and neural ...
Liyuan Yan+4 more
doaj +1 more source
The Strategy of Relationship and Interactions of Human and Herpesvirus Infections
Prevalence of herpesvirus infections in the human population reaches 80–90 %. We received numerous data of their importance not only in morbidity and mortality among newborns, but also in the formation of a variety of chronic diseases in both children ...
Ye.I. Yulish
doaj +1 more source
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV-6A/B”.
Joshua Tweedy+5 more
doaj +1 more source
Prevalence of Antibodies to Human Herpesvirus 6 in Human Immunodeficiency Virus 1-Seropositive and -Negative Intravenous Drug Addicts [PDF]
Hartwig P. Huemer+3 more
openalex +1 more source