Results 171 to 180 of about 1,058,255 (301)

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger   +10 more
wiley   +1 more source

Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern‐based approach

open access: yesCancer Cytopathology, Volume 134, Issue 1, January 2026.
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Mats Ehinger   +4 more
wiley   +1 more source

CADA Inhibits Human Immunodeficiency Virus and Human Herpesvirus 7 Replication by Down-modulation of the Cellular CD4 Receptor

open access: green, 2002
Kurt Vermeire   +13 more
openalex   +2 more sources

Identification of Potential Ferroptosis Biomarkers in Multiple Myeloma via WGCNA and Experiments

open access: yesCancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Multiple myeloma is a common malignant tumor of the hematologic system, and genetic alterations play a crucial role in its occurrence and development. Ferroptosis is an oxidative and iron‐dependent programmed cell death, which has a strong correlation with tumor development.
Yifan Wang   +7 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Immunogenicity of a BTLA Agonist Antibody (Venanprubart) in Healthy Participants, Patients with Systemic Lupus Erythematosus, and Patients with Psoriasis: Results From Three Phase 1 Studies

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Venanprubart (LY3361237), an agonist antibody to B and T lymphocyte attenuator (BTLA), was developed as a potential treatment for autoimmune disorders, including systemic lupus erythematosus (SLE) and psoriasis. We tested venanprubart in three human Phase 1 safety studies: a single ascending dose (SAD) study in healthy participants (1/2/5/15 ...
Andrew C. Vendel   +9 more
wiley   +1 more source

Definition and Distribution Analysis of Glycoprotein B Gene Alleles of Human Herpesvirus 7 [PDF]

open access: bronze, 1998
Michael Franti   +6 more
openalex   +1 more source

Trends in Incidence and Survival of Patients With Primary Effusion Lymphoma in the United States: A Population Based Cohort Study

open access: yesHematological Oncology, Volume 44, Issue 1, January 2026.
ABSTRACT Primary effusion lymphoma (PEL) is a rare and aggressive B‐cell non‐Hodgkin lymphoma (NHL) that predominantly affects patients with human immunodeficiency virus infection and is strongly associated with human herpes virus 8 (HHV‐8) infection. Due to its rarity, the current understanding of PEL's epidemiology and management is largely derived ...
John L. Vaughn   +4 more
wiley   +1 more source

Detection of Human Herpesvirus 7 DNA by Loop-Mediated Isothermal Amplification

open access: green, 2004
Tetsushi Yoshikawa   +9 more
openalex   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei   +4 more
wiley   +1 more source

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