Results 1 to 10 of about 7,818,543 (194)
Mouse Models for Human Herpesviruses [PDF]
Pathogens, 2023 More than one hundred herpesviruses have been isolated from different species so far, with nine infecting humans. Infections with herpesviruses are characterized by life-long latency and represent a significant challenge for human health.
Ivana Kutle, Anne Dittrich, Dagmar Wirth
doaj +5 more sources
Endogenous human herpesviruses 6A/B [PDF]
Journal of VirologyHuman herpesviruses 6A and 6B (HHV-6A/B) can integrate into the germline, resulting in inherited viral DNA—now proposed to be called “endogenous HHV-6A/B (eHHV-6A/B).” Present in 0.2–3% of humans, this integrated DNA is passed to offspring and may ...
Louis Flamand +17 more
doaj +6 more sources
Modulation of Endosome Function, Vesicle Trafficking and Autophagy by Human Herpesviruses [PDF]
Cells, 2021 Human herpesviruses are a ubiquitous family of viruses that infect individuals of all ages and are present at a high prevalence worldwide. Herpesviruses are responsible for a broad spectrum of diseases, ranging from skin and mucosal lesions to blindness ...
Eduardo I. Tognarelli +6 more
doaj +6 more sources
Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights [PDF]
Viruses, 2022 Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics. HHVs can induce lytic and latent infections in their host, and most of these viruses are neurotropic, with the capacity to generate severe and chronic neurological ...
Miroslava Šudomová +5 more
doaj +3 more sources
COVID-19, SARS-CoV-2 Vaccination, and Human Herpesviruses Infections [PDF]
Vaccines, 2023 There are several human herpesviruses. A common characteristic of infection by these viruses is latency, by which the virus assumes a non-replicative state, subverting the attentions of the host’s immune response.
Peter A. C. Maple
doaj +3 more sources
Viruses, 2018 Herpesviruses are common components of the human microbiome that become clinically relevant when a competent immunosurveillance is compromised, such as in transplantation.
Yessica Sánchez-Ponce +7 more
doaj +4 more sources
Human Herpesviruses Increase the Severity of Hepatitis [PDF]
Biology, 2021 Acute and chronic liver diseases are a major global public health problem; nevertheless, the etiology of 12–30% of cases remains obscure. The purpose of this research was to study the incidence of human herpesviruses (HHVs) cytomegalovirus, Epstein–Barr ...
Kirill I. Yurlov +8 more
doaj +2 more sources
The Impact of Human Herpesviruses in Clinical Practice of Inflammatory Bowel Disease in the Era of COVID-19 [PDF]
Microorganisms, 2021 Human herpesviruses (HHVs): herpes simplex virus (HSV) types 1 (HSV-1) and 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), HHV-6, HHV-7, and HHV-8, are known to be part of a family of DNA viruses that cause ...
Shuhei Hosomi +2 more
doaj +2 more sources
Evasion of Intracellular DNA Sensing by Human Herpesviruses [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Sensing of viral constituents is the first and critical step in the host innate immune defense against viruses. In mammalian cells, there are a variety of pathogen recognition receptors (PRRs) that detect diverse pathogen-associated molecular patterns ...
Debipreeta Bhowmik, Fanxiu Zhu
doaj +2 more sources
Molecular Mechanisms of Cell-to-Cell Transmission in Human Herpesviruses [PDF]
VirusesMembers of the family Orthoherpesviridae employs two distinct transmission modes: free virion release and cell-to-cell transmission. The latter enables immune evasion through multiple mechanisms, facilitating infections in skin, mucosa, and neural ...
Liyuan Yan +4 more
doaj +2 more sources