Co-expression networks in generation of induced pluripotent stem cells. [PDF]
We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for
Coppola, Giovanni +6 more
core +2 more sources
Comprehensive insight into chicken germline cells: A review
Genetic information is propagated in the progeny through germ cells. The stem cells which are precursors of these germ cells have the ability of self-renewal and can give rise to pluripotent stem cells under favorable conditions.
Malik Ahsan Ali +4 more
doaj +1 more source
Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A. [PDF]
Hemophilia A (HA) is a bleeding disorder characterized by spontaneous and prolonged hemorrhage. The disease is caused by mutations in the coagulation factor 8 gene (F8) leading to factor VIII (FVIII) deficiency.
Agu, Emmanuel +9 more
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Pluripotent Stem Cells: Current Understanding and Future Directions
Pluripotent stem cells have the ability to undergo self-renewal and to give rise to all cells of the tissues of the body. However, this definition has been recently complicated by the existence of distinct cellular states that display these features ...
Antonio Romito, Gilda Cobellis
doaj +1 more source
BackgroundCardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model.
Xiao‐Xu Qiu +12 more
doaj +1 more source
Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina +11 more
core
Apolipoprotein E4 impairs iron efflux in human induced pluripotent stem cell (iPSC)‐derived cortical neurons by reducing ferroportin on cell surface [PDF]
He Xu, Huiling Gao
openalex +1 more source
Therapeutic potential of clinical-grade human induced pluripotent stem cell-derived cardiac tissues
Hiroaki Osada +6 more
openalex +1 more source
Coating-Free Culture Medium for Establishing and Maintaining Human Induced Pluripotent Stem Cells
Chih-Yao Lin +9 more
openalex +1 more source
Temporal activation of LRH‐1 and RAR‐γ in human pluripotent stem cells induces a functional naïve‐like state [PDF]
Adeleh Taei +15 more
openalex +1 more source

