Elevated p16Ink4a Expression Enhances Tau Phosphorylation in Neurons Differentiated From Human-Induced Pluripotent Stem Cells. [PDF]
Holloway K +7 more
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Efficient derivation of functional astrocytes from human induced pluripotent stem cells (hiPSCs). [PDF]
Szeky B +12 more
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Transcriptome and epigenome dynamics of the clonal heterogeneity of human induced pluripotent stem cells for cardiac differentiation. [PDF]
Yun J +8 more
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Differentiation of human induced pluripotent stem cells into retinal pigment epithelium cells during culture on peptide-grafted hydrogels. [PDF]
Liu J +10 more
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Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation. [PDF]
Matsuo-Takasaki M +21 more
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Generation of human-induced pluripotent stem cells
Nature Protocols, 2008Pluripotent cells, such as embryonic stem cells, are invaluable tools for research and can potentially serve as a source of cell- and tissue-replacement therapy. Rejection after transplantation of cells and tissue derived from embryonic stem cells is a significant obstacle to their clinical use.
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Clinical potential of human-induced pluripotent stem cells
Cell Biology and Toxicology, 2016The recent establishment of induced pluripotent stem (iPS) cells promises the development of autologous cell therapies for degenerative diseases, without the ethical concerns associated with human embryonic stem (ES) cells. Initially, iPS cells were generated by retroviral transduction of somatic cells with core reprogramming genes.
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Glycomics of human embryonic stem cells and human induced pluripotent stem cells
Glycoconjugate Journal, 2016Most cells are coated by a dense glycocalyx composed of glycoconjugates such as glycosphingolipids, glycoproteins, and proteoglycans. The overall glycomic profile is believed to be crucial for the diverse roles of glycans, which are mediated by specific interactions that regulate cell-cell adhesion, the immune response, microbial pathogenesis, and ...
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